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rdf:type
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Description
| - Zjistili jsme, že 6-halogenované uracily substituované v pozici C5 určitými hydrofobními skupinami vykazují významnou inhibiční aktivitu vůči lidské thymidin fosforylase. Nejúčinnější látky nesou pěti nebo šestičlenný cyklický substituent v poloze C5 a atom chloru v poloze C6. (cs)
- We have discovered that 6-halouracils substituted at position C5 by certain hydrophobic groups exhibit significant inhibitory activity against human thymidine phosphorylase. The most potent compounds bear a five- or six-membered cyclic substituent at C5 and a chlorine atom attached at C6.
- We have discovered that 6-halouracils substituted at position C5 by certain hydrophobic groups exhibit significant inhibitory activity against human thymidine phosphorylase. The most potent compounds bear a five- or six-membered cyclic substituent at C5 and a chlorine atom attached at C6. (en)
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Title
| - Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase
- Objev 5-substituovaných-6-chloruracilů jako účinných inhibitorů lidské thymidin fosforylasy (cs)
- Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase (en)
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skos:prefLabel
| - Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase
- Objev 5-substituovaných-6-chloruracilů jako účinných inhibitorů lidské thymidin fosforylasy (cs)
- Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase (en)
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skos:notation
| - RIV/61388963:_____/07:00091950!RIV08-AV0-61388963
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0508), P(1QS400550501), Z(AV0Z40550506)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61388963:_____/07:00091950
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - thymidine phosphorylase inhibitors (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Medicinal Chemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Holý, Antonín
- Hřebabecký, Hubert
- Jansa, Petr
- Nencka, Radim
- Votruba, Ivan
- Tloušťová, Eva
- Masojídková, Milena
- Horská, Květoslava
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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