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rdf:type
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Description
| - CART (cocaine- and amphetamine-regulated transcript) peptidy jsou neuropeptidy, které se vyskytují v CNS a v periferii. Ukazujeme zde vazbu na 125I-CART(61-102) na potkaní tumorové buňky dřeně nadledvin PC12 linii, na celých buňkách a na jejich membránách. Tato studie prezentuje syntézu nových fragmentů peptidu CART souvisejících se strukturními smyčkami CART(61–102). Výsledky dokazují, že struktura se třemi S-S můstky je důležité pro zachování plné biologické aktivity CART peptidů. (cs)
- CART (cocaine- and amphetamine-regulated transcript) peptides are neuropeptides in the central nervous system and periphery.We report specific binding of 125I-CART(61-102) to the rat adrenal pheochromocytoma PC12 cell line, both intact cells and cell membranes. In this study, we present synthesis of several new peptide fragments corresponding to structural loops of CART(61–102).The results showed that a compact structure containing three disulfide bridges is necessary for preservation of full biological activity of CART peptides.
- CART (cocaine- and amphetamine-regulated transcript) peptides are neuropeptides in the central nervous system and periphery.We report specific binding of 125I-CART(61-102) to the rat adrenal pheochromocytoma PC12 cell line, both intact cells and cell membranes. In this study, we present synthesis of several new peptide fragments corresponding to structural loops of CART(61–102).The results showed that a compact structure containing three disulfide bridges is necessary for preservation of full biological activity of CART peptides. (en)
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Title
| - Structure-activity relationship of CART (cocaine- and amphetamine-regulated transcript) peptide fragments
- Structure-activity relationship of CART (cocaine- and amphetamine-regulated transcript) peptide fragments (en)
- Vztah mezi strukturou a aktivitou peptidu CART a jeho fragmentů (cs)
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skos:prefLabel
| - Structure-activity relationship of CART (cocaine- and amphetamine-regulated transcript) peptide fragments
- Structure-activity relationship of CART (cocaine- and amphetamine-regulated transcript) peptide fragments (en)
- Vztah mezi strukturou a aktivitou peptidu CART a jeho fragmentů (cs)
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skos:notation
| - RIV/61388963:_____/07:00088888!RIV08-AV0-61388963
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA303/05/0614), Z(AV0Z40550506)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61388963:_____/07:00088888
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - CART peptide; fragments; binding; PC12 cells (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Blechová, Miroslava
- Elbert, Tomáš
- Hlaváček, Jan
- Maixnerová, Jana
- Maletínská, Lenka
- Slaninová, Jiřina
- Železná, Blanka
- Šanda, Miloslav
- Blokešová, Darja
- Kowalczyk, W.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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