About: Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	3-(Fluoroacyloxy)chinolin-2,4(1H,3H)-diony reagují s triethylfosfitem za vzniku buď produktu Perkowovy reakce nebo odpovídajícího 4-ethoxychinolin-2(1H)-onu. U obou reakcí fluorkarboxylatový aniont je odstupující skupinou. Pro příslušný 3-(fluoiodacetoxy) derivát toto zjištění vylučuje využití intramolekulární Wittigovy-Hornerovy syntézy pro modifikaci chinolin-2,4(1H,3H)-dionů, ke kterým je připojována fluorovaná but-2-enolidová složka. (cs) 3-(Fluoroacyloxy)quinoline-2,4(1H,3H)-diones react with triethyl phosphite to afford either the product of the Perkow reaction or the corresponding 4-ethoxyquinolin-2(1H)-one. In both reactions, the fluorocarboxylate anion acts as the leaving group. For the corresponding 3-(fluoroiodoacetoxy) derivative this observation precludes the application of the intramolecular Wittig-Horner synthesis to modify quinoline-2,4(1H,3H)-diones by the annulation of a fluorinated but-2-enolide moiety. 3-(Fluoroacyloxy)quinoline-2,4(1H,3H)-diones react with triethyl phosphite to afford either the product of the Perkow reaction or the corresponding 4-ethoxyquinolin-2(1H)-one. In both reactions, the fluorocarboxylate anion acts as the leaving group. For the corresponding 3-(fluoroiodoacetoxy) derivative this observation precludes the application of the intramolecular Wittig-Horner synthesis to modify quinoline-2,4(1H,3H)-diones by the annulation of a fluorinated but-2-enolide moiety. (en)
Title	Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups (en) Omezení Wittigova-Hornerova způsobu připojení fluorobutenolidové složky k 3-hydroxychinolin-2,4(2H,3H)-dionům . Nová modifikace Perkowovy reakce zahrnující odstupující fluorované acyloxy skupiny (cs)
skos:prefLabel	Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups (en) Omezení Wittigova-Hornerova způsobu připojení fluorobutenolidové složky k 3-hydroxychinolin-2,4(2H,3H)-dionům . Nová modifikace Perkowovy reakce zahrnující odstupující fluorované acyloxy skupiny (cs)
skos:notation	RIV/61388963:_____/07:00085693!RIV08-AV0-61388963
http://linked.open.../vavai/riv/strany	10549;10561
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/07/0320), Z(AV0Z40550506), Z(MSM 223100001), Z(MSM6046137301), Z(MSM7088352101)
http://linked.open...iv/cisloPeriodika	42
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Pomeisl, Karel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	431086
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/07:00085693
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Wittig-Horner synthesis; Fluorofuranone; but-2-enolide; cytostatic activity (en)
http://linked.open.../riv/klicoveSlovo	Fluorofuranone Wittig-Horner synthesis but-2-enolide cytostatic activity
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[33EE66144FC5]
http://linked.open...i/riv/nazevZdroje	Tetrahedron
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Transformations of 3-hydroxy, 3-amino, and 3-thiocyanatoquinoline-2,4(1H,3H)-diones to novel heterocyclic systems
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	63
http://linked.open...iv/tvurceVysledku	Havlíček, J. Čejka, J. Paleta, O. Kvíčala, J. Pomeisl, Karel Klásek, A. Kafka, S. Kubelka, V.
http://linked.open...n/vavai/riv/zamer	Catalytic processes in chemistry and chemical technology Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Multifunctional Composite Systems Based on Natural and Synthetic Polymers http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20223100001
issn	0040-4020
number of pages	13 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software