About: Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues

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About: Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Attempts to demonstrate and interpret differences between subunits forming biologically active oligomers of low-(calf spleen) and high-molecular mass (E. coli) purine nucleoside phosphorylases (PNP) yielded new crystal structures of both enzymes complexed with ground-state analogue ligands in space groups and with two full trimers and one full hexamer in the asymmetric unit, respectively. Attempts to demonstrate and interpret differences between subunits forming biologically active oligomers of low-(calf spleen) and high-molecular mass (E. coli) purine nucleoside phosphorylases (PNP) yielded new crystal structures of both enzymes complexed with ground-state analogue ligands in space groups and with two full trimers and one full hexamer in the asymmetric unit, respectively. (en) Byla studována krystalová struktura trimerní purinnukleosidfosforylázy z telecí sleziny v komplexu s 2,6-diamino-(S)-9-[2-(phosphonomethoxy)propyl]purinem. Mezi subjednotkami nebyly nalezeny žádné rozdíly. (cs)
Title	Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues (en) Pokusy o rozlišení podjednotek trimerních a hexamerních forem purinnukleosidfosforylázy pomocí krystalové struktury komplexů purinových bází nukleosidů, acyklonukleosidů a jejich fosfonátových analogů (cs)
skos:prefLabel	Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues (en) Pokusy o rozlišení podjednotek trimerních a hexamerních forem purinnukleosidfosforylázy pomocí krystalové struktury komplexů purinových bází nukleosidů, acyklonukleosidů a jejich fosfonátových analogů (cs)
skos:notation	RIV/61388963:_____/05:00023146!RIV06-AV0-61388963
http://linked.open.../vavai/riv/strany	133;141
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z40550506)
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Holý, Antonín
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	513301
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/05:00023146
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	purine nucleoside phosphorylases; purine bases; acyclonucleosides (en)
http://linked.open.../riv/klicoveSlovo	purine bases acyclonucleosides purine nucleoside phosphorylases
http://linked.open...ontrolniKodProRIV	[4832C77EFB39]
http://linked.open...v/mistoKonaniAkce	Špindlerův Mlýn
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	Chemistry of Nucleic Acid Components
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...iv/tvurceVysledku	Holý, Antonín Frank, J. Steiner, T. Bzowska, A. Koellner, G. Raszewski, G. Stroh, A. Wielgus-Kutrowska, B. Antosiewicz, J. Dlugosz, M. Olasek, M. Stepniak, K.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2005-09-03 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
number of pages	9 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Ústav organické chemie a biochemie AV ČR
https://schema.org/isbn	80-86241-25-4

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