About: 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?

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About: 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Synthesis and hybridization selectivity of 9-mers 5’-d(GTG ATA TGC)-3’ (T means modified units) containing both hydroxyphosphonate and phosphodiester 2’-5’ internucleotide linkages toward complementary DNA and RNA counterpart were investigated. Synthesis and hybridization selectivity of 9-mers 5’-d(GTG ATA TGC)-3’ (T means modified units) containing both hydroxyphosphonate and phosphodiester 2’-5’ internucleotide linkages toward complementary DNA and RNA counterpart were investigated. (en) Byly syntetizovány 9-mery 5’-d(GTG ATA TGC)-3’ (T je modifikovaná jednotka), které obsahovaly jak hydroxyfosfonátové tak fosfodiesterové 2’-5’ internukleotidové vazby a byla zkoumána jejich hybridizační selektivita vůči DNA and RNA. (cs)
Title	2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? (en) Oligo-3'-deoxynukleotidy s chirální alfa-hydroxyfosfonátovou 2',5' internukleotidovou vazbou: zlepšení hybridizační selektivity vůči RNA? (cs)
skos:prefLabel	2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? (en) Oligo-3'-deoxynukleotidy s chirální alfa-hydroxyfosfonátovou 2',5' internukleotidovou vazbou: zlepšení hybridizační selektivity vůči RNA? (cs)
skos:notation	RIV/61388963:_____/05:00022984!RIV06-GA0-61388963
http://linked.open.../vavai/riv/strany	421;422
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP203/04/P273), P(IAA4055101), Z(AV0Z40550506)
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Rosenberg, Ivan Buděšínský, Miloš Králíková, Šárka Páv, Ondřej Liboska, Radek
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	552700
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/05:00022984
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	oligonucleotides; hydroxyphosphonates; 2'-5' linkage (en)
http://linked.open.../riv/klicoveSlovo	oligonucleotides 2'-5' linkage hydroxyphosphonates
http://linked.open...ontrolniKodProRIV	[438072D3B41D]
http://linked.open...v/mistoKonaniAkce	Špindlerův Mlýn
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	Chemistry of Nucleic Acid Components
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Phosphonate-based 2'-5' oligoadenylate analogs: a novel metabolically stable potential activators of RNase L. Modified oligonucleotides derived from 5´-substituted nucleoside 5´-C-phosphonates: synthesis and hybridization properties
http://linked.open...UplatneniVysledku	2005
http://linked.open...iv/tvurceVysledku	Buděšínský, Miloš Rosenberg, Ivan Králíková, Šárka Páv, Ondřej Liboska, Radek
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2005-09-03 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Ústav organické chemie a biochemie AV ČR
https://schema.org/isbn	80-86241-25-4

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