About: Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages

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About: Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	9-alkyl and 9-heteroalkyl substituted derivatives of the 2-amino-6-guanidinopurine were synthesized. The inhibitory activity of thus-prepared compounds on LPS+IFN-gamma-induced NO production in murine macrophages was examined. 9-alkyl and 9-heteroalkyl substituted derivatives of the 2-amino-6-guanidinopurine were synthesized. The inhibitory activity of thus-prepared compounds on LPS+IFN-gamma-induced NO production in murine macrophages was examined. (en) Byly syntetizovány 9-alkyl a 9-heteroalkyl substituované deriváty 2-amino-6-guanidinopurinu, které byly podrobeny testům, při kterých byl testován jejich inhibiční účinek v systému LPS+IFN-gamma-indukované produkce NO v myších makrofágách. (cs)
Title	Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages (en) Syntéza 9-alkyl a 9-heteroalkyl substituovaných 2-amino-6-guanidinopurinů a jejich vliv na produkci NO v makrofágách (cs)
skos:prefLabel	Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages (en) Syntéza 9-alkyl a 9-heteroalkyl substituovaných 2-amino-6-guanidinopurinů a jejich vliv na produkci NO v makrofágách (cs)
skos:notation	RIV/61388963:_____/05:00021684!RIV06-MSM-61388963
http://linked.open.../vavai/riv/strany	2917;2926
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/03/1470), P(IBS4055109), P(OC D13.20), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Česnek, Michal Holý, Antonín Masojídková, Milena
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	545777
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/05:00021684
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	6-guanidinopurines; guanidino derivatives; immunomodulatory activity (en)
http://linked.open.../riv/klicoveSlovo	6-guanidinopurines guanidino derivatives immunomodulatory activity
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[E7CFFBC0F933]
http://linked.open...i/riv/nazevZdroje	Bioorganic Medical Chemistry
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Immunomodulatory activity of adenosine receptor systém and its role in immunobiological effects of antiviral acyclic nucleoside phosphonates http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20D13.20 Acyclic nucleoside phosponates with antineoplastic activity
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Holý, Antonín Zídek, Zdeněk Česnek, Michal Masojídková, Milena
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0968-0896
number of pages	10 (xsd:int)

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