About: Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The chemical characteristics of the polar parts of phospholipids were investigated by using infrared (IR) spectroscopy and theoretical calculations with water as a probe molecule. The main process appearing upon progressive hydration is unfolding of methylphosphocholine (MePC) molecules that are closely packed in isolated state. The stepwise disruption of the intramolecular hydrogen bonds stabilizing the original packed structure of MePC is connected in substantial changes in vibrational properties of MePC. The mechanism of hydration-driven conformational changes occurring in MePC could be transferred to other zwitterions with relevant internal C-H...O hydrogen bonds. The chemical characteristics of the polar parts of phospholipids were investigated by using infrared (IR) spectroscopy and theoretical calculations with water as a probe molecule. The main process appearing upon progressive hydration is unfolding of methylphosphocholine (MePC) molecules that are closely packed in isolated state. The stepwise disruption of the intramolecular hydrogen bonds stabilizing the original packed structure of MePC is connected in substantial changes in vibrational properties of MePC. The mechanism of hydration-driven conformational changes occurring in MePC could be transferred to other zwitterions with relevant internal C-H...O hydrogen bonds. (en) Charakteristiky polárních částí fosfolipidů a jejich interakce s vodou byly studovány pomocí infračervené spektroskopie a teoretických výpočtů. Hlavní proces, k němuž dochází při postupné hydrataci, je konformační změna molekuly metylfosfocholinu z těsně sbalené, která je v isolovaném stavu, na rozbalenou díky porušení intramolekulových vodíkových vazeb. Tato konformační změna je doprovázena dobře pozorovatelnými změnami ve vibračních charakteristikách. Naznačený mechanismus konformačních změn indukovaných hydratací je pravděpodobně obecně platný pro všechny zwitterionty s relevatními intramolekulovými vodíkovými vazbami. (cs)
Title	Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids Hydratací indukované změny struktury a vibračních vlastností methylfosfocholinu, model membránového lipidu (cs) Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids (en)
skos:prefLabel	Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids Hydratací indukované změny struktury a vibračních vlastností methylfosfocholinu, model membránového lipidu (cs) Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids (en)
skos:notation	RIV/61388963:_____/05:00021197!RIV06-MSM-61388963
http://linked.open.../vavai/riv/strany	15126;15134
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/05/0009), P(LC512), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Hobza, Pavel Mrázková, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	523938
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/05:00021197
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hydrogen bonding; zwitterions; vibrational properties of hydrogen bonded complexes (en)
http://linked.open.../riv/klicoveSlovo	hydrogen bonding zwitterions vibrational properties of hydrogen bonded complexes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2CCDA5B8BBA0]
http://linked.open...i/riv/nazevZdroje	Journal of Physical Chemistry B
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for biomolecules and complex molecular systems Structure and dynamics of DNA nitrogeneous bases, base pairs, oligonucleotides and their complexes with water, ions and drugs
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	109
http://linked.open...iv/tvurceVysledku	Hobza, Pavel Mrázková, Eva Gauger, D. R. Pohle, W. Bohl, M.
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	1520-6106
number of pages	9 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 24 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software