About: 6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity

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About: 6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Acyclické nukleosidfosfonáty pyrimidinů substituovaných aminoskupinami v C-2 a C-4 navázanými linked at the C-6 position to (S)-[3-hydroxy-2-(fosfonomethoxy)-propoxy], 2-(fosfonomethoxy)ethoxy or (R)-[2-(fosfonomethoxy)propoxy mají spektrum účinků paraátů purinů (cs) Acyclic nucleoside phosphonate derivatives containing a pyrimidine base preferably bearing amino groups at C-2 and C-4 and linked at the C-6 position to (S)-[3-hydroxy-2-(phosphonomethoxy)-propoxy], 2-(phosphonomethoxy)ethoxy or (R)-[2-(phosphonomethoxy)proxy] (PMPO), display an antiviral spectrum closely mimicking that of the parental (S)-HPMP-, PME- and (R)-PMP- purine derivatives Acyclic nucleoside phosphonate derivatives containing a pyrimidine base preferably bearing amino groups at C-2 and C-4 and linked at the C-6 position to (S)-[3-hydroxy-2-(phosphonomethoxy)-propoxy], 2-(phosphonomethoxy)ethoxy or (R)-[2-(phosphonomethoxy)proxy] (PMPO), display an antiviral spectrum closely mimicking that of the parental (S)-HPMP-, PME- and (R)-PMP- purine derivatives (en)
Title	6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity 6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity (en) 6-[2-(Fosfonomethoxy)alkoxy]-2,4-diaminopyrimidiny: nová třída pyrimidinových acyklických nukleosidfosfonátů s protivirovým účinkem (cs)
skos:prefLabel	6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity 6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity (en) 6-[2-(Fosfonomethoxy)alkoxy]-2,4-diaminopyrimidiny: nová třída pyrimidinových acyklických nukleosidfosfonátů s protivirovým účinkem (cs)
skos:notation	RIV/61388963:_____/04:00102878!RIV/2005/AV0/A57005/N
http://linked.open.../vavai/riv/strany	1321;1327
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IBS4055109), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	8/9
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Hocková, Dana Holý, Antonín
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	596735
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/04:00102878
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	herpesviruses;poxviruses;hepadnaviruses (en)
http://linked.open.../riv/klicoveSlovo	herpesviruses poxviruses hepadnaviruses
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[372580E77001]
http://linked.open...i/riv/nazevZdroje	Nucleosides, Nucleotides & Nucleic Acids
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Acyclic nucleoside phosponates with antineoplastic activity
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Andrei, G. Balzarini, J. Holý, Antonín Hocková, Dana Snoeck, R. De Clercq, E. Naesens, L. Pannecouque, C.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	1525-7770
number of pages	7 (xsd:int)

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