About: Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide

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About: Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Molecular dynamics was used to examine differences in the conformational behavior of two classes of tetravalent Multiple Antigen Glycopeptides (MAG) differring by the gamma-Abu insert in the structure of the oligolysine core. A distinct behavior of the constructs was observed already during the first steps of the modeled synthesis suggesting that the character as well as the length of the insert has a major impact on the spatial characteristics of the dendritic molecules Molecular dynamics was used to examine differences in the conformational behavior of two classes of tetravalent Multiple Antigen Glycopeptides (MAG) differring by the gamma-Abu insert in the structure of the oligolysine core. A distinct behavior of the constructs was observed already during the first steps of the modeled synthesis suggesting that the character as well as the length of the insert has a major impact on the spatial characteristics of the dendritic molecules (en) Konformační chování dvou tříd tetravalentních antigenních glykopeptidů (MAG) lišících se o (-amino máselný insert ve struktuře polylysinového jádra během syntézy na pevné fázi bylo studováno pomocí metod molekulární dynamiky. Odlišné chování těchto dvou tříd, které ukazuje, že charakter a délka aminokyselinového insertu mají hlavní vliv na prostorové charakteristiky dendrimerních molekul, bylo pozorováno již během prvních stupňů modelované syntézy (cs)
Title	Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide (en) Molekulárně dynamická studie vlivu (-amino máselného zbytku na konformační chování glykopeptidových dendrimerů založených na oligolysinovém stromečku v N, N'-dimethylformamidu (cs)
skos:prefLabel	Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide Molecular dynamics study of the effect of the gamma-Abu insert on the conformational behavior of the glycopeptide dendrimers based on the oligolysine scaffold in N, N'-dimethylformamide (en) Molekulárně dynamická studie vlivu (-amino máselného zbytku na konformační chování glykopeptidových dendrimerů založených na oligolysinovém stromečku v N, N'-dimethylformamidu (cs)
skos:notation	RIV/61388963:_____/04:00102845!RIV/2005/GA0/A57005/N
http://linked.open.../vavai/riv/strany	79;90
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA303/01/0690), P(LN00A032), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Vepřek, Pavel Ježek, Jan Vondrášek, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	574379
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/04:00102845
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	multiple antigen glycopeptides; Tn antigen; GalNAc (en)
http://linked.open.../riv/klicoveSlovo	GalNAc multiple antigen glycopeptides Tn antigen
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[DAA038B64637]
http://linked.open...i/riv/nazevZdroje	Journal of Biomolecular Structure & Dynamics
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthetic multiple antigenic glycopeptides (MAG) containing mucine antigenic determinants - potential diagnostics and cancer vaccines. Structure and dynamics of complex molecular systems and biomolecules
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Ježek, Jan Vondrášek, Jiří Vepřek, Pavel Trnka, T.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0739-1102
number of pages	12 (xsd:int)

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