About: Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity

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About: Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Neurosteroidy, které působí prostřednictvím receptoru gama-aminomáselné kyseliny, mají hydroxylovou skupinu v posici 3. Zjistili jsme, že neuronální aktivita zůstává i po nahrazení této hydroxylové skupiny aminoskupinou (cs) Neurosteroids, acting via gamma-aminobutyric receptor, have a hydroxyl in the position 3 of the pregnane skeleton. We have found that the neuronal activity is retained if an amino group substitutes for the hydroxyl Neurosteroids, acting via gamma-aminobutyric receptor, have a hydroxyl in the position 3 of the pregnane skeleton. We have found that the neuronal activity is retained if an amino group substitutes for the hydroxyl (en)
Title	Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity (en) Účinky 3alfa-amino-5alfa-pregnan-20-onu na GABA A receptor: Syntéza, aktivita a cytotoxicita (cs)
skos:prefLabel	Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity Effects of 3alpha-amino-5alpha-pregnan-20-one on GABA A receptor: Synthesis, activity and cytotoxicity (en) Účinky 3alfa-amino-5alfa-pregnan-20-onu na GABA A receptor: Syntéza, aktivita a cytotoxicita (cs)
skos:notation	RIV/61388963:_____/04:00102432!RIV/2005/AV0/A57005/N
http://linked.open.../vavai/riv/strany	1506;1516
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IBS5011007), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Matyáš, Libor Kasal, Alexander
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	562210
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/04:00102432
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	receptor;steroids;neurosteroids (en)
http://linked.open.../riv/klicoveSlovo	steroids receptor neurosteroids
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[6390214F4F29]
http://linked.open...i/riv/nazevZdroje	Collection of Czechoslovak Chemical Communications
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthesis and evaluation of neurosteroids as possible antiepileptics
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	69
http://linked.open...iv/tvurceVysledku	Kasal, Alexander Matyáš, Libor Riera, Z. B. Sunol, C. E.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0010-0765
number of pages	11 (xsd:int)

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