About: PMEDAP and its N 6 -substituted derivatives: genotoxic effect and apoptosis in vitro conditions.     Goto   Sponge   NotDistinct   Permalink

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  • The genotoxic and antiproliferative effect of compounds was investigated on CCRF-CEM, HeLaS3, MRC-5 and Reh cell lines. PMEG and cypr-PMEDAP exhibit high genotoxic and cytostatic effect. PMEDAP and its N 6 -substituted derivatives Me 2 NEt-PMEDAP, allyl-PMEDAP and Me 2 -PMEDAP are considerably less genotoxic.
  • The genotoxic and antiproliferative effect of compounds was investigated on CCRF-CEM, HeLaS3, MRC-5 and Reh cell lines. PMEG and cypr-PMEDAP exhibit high genotoxic and cytostatic effect. PMEDAP and its N 6 -substituted derivatives Me 2 NEt-PMEDAP, allyl-PMEDAP and Me 2 -PMEDAP are considerably less genotoxic. (en)
Title
  • PMEDAP and its N 6 -substituted derivatives: genotoxic effect and apoptosis in vitro conditions.
  • PMEDAP and its N 6 -substituted derivatives: genotoxic effect and apoptosis in vitro conditions. (en)
skos:prefLabel
  • PMEDAP and its N 6 -substituted derivatives: genotoxic effect and apoptosis in vitro conditions.
  • PMEDAP and its N 6 -substituted derivatives: genotoxic effect and apoptosis in vitro conditions. (en)
skos:notation
  • RIV/61388963:_____/03:57030422!RIV/2004/AV0/A57004/N
http://linked.open.../vavai/riv/strany
  • 4933;4940
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  • P(IBS4055109), Z(AV0Z4055905), Z(MSM 111100004)
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  • N/A
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  • 621147
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  • RIV/61388963:_____/03:57030422
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  • N 6 -substituted derivatives of PMEDAP; genotoxicity; apoptosis (en)
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  • GR - Řecká republika
http://linked.open...ontrolniKodProRIV
  • [A5AEFDB85D6E]
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  • Anticancer Research
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  • 23
http://linked.open...iv/tvurceVysledku
  • Eckschlager, T.
  • Holý, Antonín
  • Votruba, Ivan
  • Trka, J.
  • Otová, B.
  • Bílá, V.
  • Krejčí, O.
  • Valeriánová, M.
  • Hanzalová, J.
http://linked.open...n/vavai/riv/zamer
issn
  • 0250-7005
number of pages
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