About: Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.

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About: Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The major mechanism of antiviral action of acyclic nucleoside phosphonates is inhibition of virus-induced DNA polymerases and of reverse transcriptases. They inhibit eukaryotic DNA polymerases, as well. Their suppressive effects on proliferation of mammalian lymphocytes differ greatly in dependence on the chemical structure. No tight correlation between the cytostatic and antiviral effects has been observed. The major mechanism of antiviral action of acyclic nucleoside phosphonates is inhibition of virus-induced DNA polymerases and of reverse transcriptases. They inhibit eukaryotic DNA polymerases, as well. Their suppressive effects on proliferation of mammalian lymphocytes differ greatly in dependence on the chemical structure. No tight correlation between the cytostatic and antiviral effects has been observed. (en)
Title	Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. (en)
skos:prefLabel	Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. (en)
skos:notation	RIV/61388963:_____/03:19033002!RIV/2004/GA0/A57004/N
http://linked.open.../vavai/riv/strany	246;253
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/00/0048), Z(AV0Z4055905), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Holý, Antonín
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	602561
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/03:19033002
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	acyclic nucleoside phosphonates (en)
http://linked.open.../riv/klicoveSlovo	acyclic nucleoside phosphonates
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2E31D5D96E45]
http://linked.open...i/riv/nazevZdroje	Toxicology and Applied Pharmacology
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Immune mechanisms of action of antiviral acyclic nucleoside phosphonates (ANP)
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	192
http://linked.open...iv/tvurceVysledku	Holý, Antonín Zídek, Zdeněk Potměšil, Petr
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy Chemical principles of selected biological phenomena in medicine and ecology
issn	0041-008X
number of pages	8 (xsd:int)

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