About: Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates.

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About: Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Anovel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy) ethoxy (PMEO) or a 2-(phosphonomethoxy)propoxy (PMPO) group at C-6. The 6-PMEO 2,4-diaminopyrimidine and 6-PMPO 2,4-diaminopyrimidine derivatives showed potent activity HIV. Anovel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy) ethoxy (PMEO) or a 2-(phosphonomethoxy)propoxy (PMPO) group at C-6. The 6-PMEO 2,4-diaminopyrimidine and 6-PMPO 2,4-diaminopyrimidine derivatives showed potent activity HIV. (en)
Title	Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates. Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates. (en)
skos:prefLabel	Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates. Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates. (en)
skos:notation	RIV/61388963:_____/02:57020240!RIV/2003/AV0/A57003/N
http://linked.open.../vavai/riv/strany	2185;2193
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GV203/96/K001), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Holý, Antonín
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	638597
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/02:57020240
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nucleoside phosphonates (en)
http://linked.open.../riv/klicoveSlovo	nucleoside phosphonates
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[4947FA5B9FD0]
http://linked.open...i/riv/nazevZdroje	Antimicrobial Agents and Chemotherapy
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of Antiviral and Anticancer Drugs with Acyclic Nucleotide Structure: Rational Design Based on Their Interference with Cellular Metabolism.
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	46
http://linked.open...iv/tvurceVysledku	Balzarini, J. Holý, Antonín De Clercq, E. Perno, C. F. Aquaro, S. Egberink, H. Pannecouque, C.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0066-4804
number of pages	9 (xsd:int)

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