About: Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene

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About: Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The influence of single-layer graphene produced by chemical vapor deposition on human osteoblast cells under different conditions was studied. Measurements probed the ability of cells to adhere and proliferate on graphene compared with SiO2/Si substrates and standard tissue culture plastic when cells were incubated for the first 2 h in the presence or the absence of fetal bovine serum (FBS), thus influencing the initial, direct interaction of cells with the substrate. It was found that after 48 h of human osteoblast incubation on graphene films, there were a comparable number of cells of a similar size irrespective of the presence or the absence of serum proteins. On the other hand, a strong initial influence through the presence of FBS proteins on cell number and cell size was observed in the case of the SiO2/Si substrate and control plastic. Thus, our study showed that the initial presence/absence of FBS in the medium does not determine cell fate in the case of a graphene substrate, which is very unusual and different from the behavior of cells on other materials. The influence of single-layer graphene produced by chemical vapor deposition on human osteoblast cells under different conditions was studied. Measurements probed the ability of cells to adhere and proliferate on graphene compared with SiO2/Si substrates and standard tissue culture plastic when cells were incubated for the first 2 h in the presence or the absence of fetal bovine serum (FBS), thus influencing the initial, direct interaction of cells with the substrate. It was found that after 48 h of human osteoblast incubation on graphene films, there were a comparable number of cells of a similar size irrespective of the presence or the absence of serum proteins. On the other hand, a strong initial influence through the presence of FBS proteins on cell number and cell size was observed in the case of the SiO2/Si substrate and control plastic. Thus, our study showed that the initial presence/absence of FBS in the medium does not determine cell fate in the case of a graphene substrate, which is very unusual and different from the behavior of cells on other materials. (en)
Title	Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene (en)
skos:prefLabel	Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene Influence of the fetal bovine serum proteins on the growth of human osteoblast cells on graphene (en)
skos:notation	RIV/61388955:_____/12:00384165!RIV13-GA0-61388955
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GAP204/10/1677), P(GAP208/12/1062), P(IAA400400911), P(KAN115600801), P(KAN200100801), P(KAN400100701), P(ME09060), Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kalbáč, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...dnocenehoVysledku	141622
http://linked.open...ai/riv/idVysledku	RIV/61388955:_____/12:00384165
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	human osteoblast; graphene; fetal bovine serum (en)
http://linked.open.../riv/klicoveSlovo	graphene fetal bovine serum human osteoblast
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[985CDE45E12B]
http://linked.open...i/riv/nazevZdroje	Journal of Biomedical Materials Research. Part A
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Spectroscopy and spectroelectrochemistry of chemically doped carbon nanostructures Magnetic properties of carbon nanostructures in neutral and doped state New technologies of preparation and exploitation of iron oxide-based nanoparticles for environmental, industrial and medical applications Bioactive Biocompatible Surfaces and Novel Nanostructured Composites for Applications to Medicine and Drug Delivery Functional hybrid nanosystems of semiconductors and metals with organic materials (FUNS) Spectroscopy and spectroelectrochemistry of graphene and graphene multilayers The electrochemical gating of individual and bundled Single Walled Carbon Nanotubes
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	100A
http://linked.open...iv/tvurceVysledku	Brož, A. Kalbáč, Martin Kalbáčová, M.
http://linked.open...ain/vavai/riv/wos	000309063400016
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	1549-3296
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/jbm.a.34231

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