About: Supplementation of Creatine in Sportsman with Hyperhomocysteinemia

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	One month's administration of creatine (CR) in the dose of 5 g/day to 11 young active sportsmen affected their daily amount of CR and creatinine excreted into urine. The probands were divided into 4 groups, according to the amount of CR found in urine, and of folates and of vitamin B12 determined in blood. The ganges of folates and vitamin B12 were mutually reciprocal. Each group utilized CR as donor of one- and two-carbon (1C and 2C) units by means of homocysteine (HoCySH), folates, and vitamin B12, in different metabolic pathways. In 10 men the CR administration was accompanied by an increase of HoCySH level in blood, while for the last man, with accidentally discovered hyperhomocysteinemia, after the month's CR administration the HoCySH level dropped by 50 %. One month's administration of creatine (CR) in the dose of 5 g/day to 11 young active sportsmen affected their daily amount of CR and creatinine excreted into urine. The probands were divided into 4 groups, according to the amount of CR found in urine, and of folates and of vitamin B12 determined in blood. The ganges of folates and vitamin B12 were mutually reciprocal. Each group utilized CR as donor of one- and two-carbon (1C and 2C) units by means of homocysteine (HoCySH), folates, and vitamin B12, in different metabolic pathways. In 10 men the CR administration was accompanied by an increase of HoCySH level in blood, while for the last man, with accidentally discovered hyperhomocysteinemia, after the month's CR administration the HoCySH level dropped by 50 %. (en)
Title	Supplementation of Creatine in Sportsman with Hyperhomocysteinemia Supplementation of Creatine in Sportsman with Hyperhomocysteinemia (en)
skos:prefLabel	Supplementation of Creatine in Sportsman with Hyperhomocysteinemia Supplementation of Creatine in Sportsman with Hyperhomocysteinemia (en)
skos:notation	RIV/61388955:_____/09:00334284!RIV10-AV0-61388955
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/07/1195), P(IAA400400806), Z(AV0Z40400503), Z(MSM 115100002), Z(MSM0021620864)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Heyrovský, Michael Navrátil, Tomáš
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...dnocenehoVysledku	344723
http://linked.open...ai/riv/idVysledku	RIV/61388955:_____/09:00334284
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	creatine (CR); creatinine; folates; homocysteine (en)
http://linked.open.../riv/klicoveSlovo	folates homocysteine creatine (CR) creatinine
http://linked.open...ontrolniKodProRIV	[E95BE0100F14]
http://linked.open...v/mistoKonaniAkce	Praha
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	Atherosklerosa 2009
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Transport of Charged and Uncharged Species across Models of Biological Membranes Analysis of DNA structure and interactions using electrochemical techniques and chemical probes. Novel techniques and sensors for DNA damage detection
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Kohlíková, E. Navrátil, Tomáš Petr, M. Heyrovský, Michael Pelclová, D. Žák, J. Přistoupil, T. I. Přistoupilová, K.
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2009-09-09 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Struktura, reaktivita a dynamika molekulárních a biomolekulárních systémů: teorie, experiment, aplikace Aktivní životní styl v biosociálním kontextu http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20115100002
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Univerzita Karlova v Praze. 1. lékařská fakulta. IV. interní klinika
https://schema.org/isbn	978-80-254-5389-6

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