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Description
  • V této práci se studují vlastnosti smíšených kationických membrán studované pomocí fluorescenční relaxace rozpouštědla. (cs)
  • The need for detailed biophysical description of cationic lipid membranes, which are commonly used as gene transfection vectors, led us to study the properties of mixed cationic/zwitterionic lipid bilayers. Fluorescence solvent relaxation measurements of 6-dodecanoyl-2-dimethylaminonaphthalene (Laurdan) incorporated in a membrane consisting of cationic dimyristoyltrimethylammoniumpropane (DMTAP) and zwitterionic dimyristoylphosphatidylcholine (DMPC) were performed. The obtained results are compared with a recently measured system consisting of dioleoyltrimethylammoniumpropane (DOTAP) and dioleoylphosphatidylcholine (DOPC) (Jurkiewicz et al. Langmuir 22:8741-8749, 2006). The similar nonmonotonic dependence of the relaxation kinetics on cationic lipid content in the membrane was present for both systems.
  • The need for detailed biophysical description of cationic lipid membranes, which are commonly used as gene transfection vectors, led us to study the properties of mixed cationic/zwitterionic lipid bilayers. Fluorescence solvent relaxation measurements of 6-dodecanoyl-2-dimethylaminonaphthalene (Laurdan) incorporated in a membrane consisting of cationic dimyristoyltrimethylammoniumpropane (DMTAP) and zwitterionic dimyristoylphosphatidylcholine (DMPC) were performed. The obtained results are compared with a recently measured system consisting of dioleoyltrimethylammoniumpropane (DOTAP) and dioleoylphosphatidylcholine (DOPC) (Jurkiewicz et al. Langmuir 22:8741-8749, 2006). The similar nonmonotonic dependence of the relaxation kinetics on cationic lipid content in the membrane was present for both systems. (en)
Title
  • Properties of mixed cationic membranes studied by fluorescence solvent relaxation
  • Properties of mixed cationic membranes studied by fluorescence solvent relaxation (en)
  • Vlastnosti smíšených kationických membrán studované pomocí fluorescenční relaxace rozpouštědla (cs)
skos:prefLabel
  • Properties of mixed cationic membranes studied by fluorescence solvent relaxation
  • Properties of mixed cationic membranes studied by fluorescence solvent relaxation (en)
  • Vlastnosti smíšených kationických membrán studované pomocí fluorescenční relaxace rozpouštědla (cs)
skos:notation
  • RIV/61388955:_____/08:00316906!RIV09-AV0-61388955
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA400400503), P(LC06063), Z(AV0Z40400503)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 390503
http://linked.open...ai/riv/idVysledku
  • RIV/61388955:_____/08:00316906
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • time-resolved emission spectroscopy; solvent relaxation; membrane interface (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [776D1208F269]
http://linked.open...i/riv/nazevZdroje
  • Journal of Fluorescence
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 18
http://linked.open...iv/tvurceVysledku
  • Hof, Martin
  • Jurkiewicz, Piotr
  • Olžyńska, Agnieszka
http://linked.open...ain/vavai/riv/wos
  • 000259187600021
http://linked.open...n/vavai/riv/zamer
issn
  • 1053-0509
number of pages
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