About: A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity     Goto   Sponge   NotDistinct   Permalink

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  • A study has been carried out, involving three healthy volunteers, of the ammonia levels in breath exhaled via the mouth and via the nose and in the static oral cavity using on-line, selected ion flow tube mass spectrometry (SIFT-MS), obviating the problems associated with sample collection of ammonia. The unequivocal conclusion drawn is that the ammonia appearing in the mouth-exhaled breath of the three volunteers is largely generated in the oral cavity and that the ammonia originating at the alveolar interface in the lungs is typically at levels less than about 100 parts-per-billion, which is a small fraction of the total breath ammonia. This leads to the recommendation that exhaled breath analyses should focus on nose-exhaled breath if the objective is to use breath analysis to investigate systemic, metabolic disease.
  • A study has been carried out, involving three healthy volunteers, of the ammonia levels in breath exhaled via the mouth and via the nose and in the static oral cavity using on-line, selected ion flow tube mass spectrometry (SIFT-MS), obviating the problems associated with sample collection of ammonia. The unequivocal conclusion drawn is that the ammonia appearing in the mouth-exhaled breath of the three volunteers is largely generated in the oral cavity and that the ammonia originating at the alveolar interface in the lungs is typically at levels less than about 100 parts-per-billion, which is a small fraction of the total breath ammonia. This leads to the recommendation that exhaled breath analyses should focus on nose-exhaled breath if the objective is to use breath analysis to investigate systemic, metabolic disease. (en)
  • Koncentrace amoniaku v dechu zdravých dobrovolníků byla určena pomocí hmotnostní spektrometrie v proudové trubici s vybranými ionty (SIFT-MS). Měření bylo prováděno přímo v proudu vzduchu vydechovaného ústy, nosem a odebíraného z uzavřené ústní dutiny. Jednoznačným závěrem je, že převážná část amoniaku přítomného ve vzduchu vydechovaném ústy je produkována v ústní dutině a že alveolární koncentrace amoniaku je menší než 100 ppb. Závěrem je doporučení provádět analýzu amoniaku vydechovaného nosem, pokud je cílem stanovení systemické metabolické poruchy. (cs)
Title
  • A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity
  • Analýza amoniaku v dechu exhalovaném ústy a nosem a vzduchu v dutině ústní pomocí hmotnostní spektrometrie v proudové trubici s vybranými ionty (SIFT-MS) (cs)
  • A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity (en)
skos:prefLabel
  • A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity
  • Analýza amoniaku v dechu exhalovaném ústy a nosem a vzduchu v dutině ústní pomocí hmotnostní spektrometrie v proudové trubici s vybranými ionty (SIFT-MS) (cs)
  • A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity (en)
skos:notation
  • RIV/61388955:_____/08:00315002!RIV09-AV0-61388955
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z40400503)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 354486
http://linked.open...ai/riv/idVysledku
  • RIV/61388955:_____/08:00315002
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • SIFT-MS; oral cavity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [24D2FAEB0E21]
http://linked.open...i/riv/nazevZdroje
  • Rapid Communications in Mass Spectrometry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 22
http://linked.open...iv/tvurceVysledku
  • Smith, D.
  • Španěl, Patrik
  • Wang, T.
  • Pysanenko, A.
http://linked.open...ain/vavai/riv/wos
  • 000254593700005
http://linked.open...n/vavai/riv/zamer
issn
  • 0951-4198
number of pages
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