About: No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C

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About: No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	No differences were found in the frequencies of each particular allele of both genes, between HCV patients and a control group (p > 0.05). Furthermore, no association was detected (p > 0.05) between either the HMOX1 or the UGT1A1 promoter variants and the individual histological stages of liver disease in the HCV positive patients. Finally, no differences in the HMOX1 and UGT1A1 genotype prevalence rates were found between pre-cirrhotic and cirrhotic patients (p > 0.05). Based on our data, microsatellite variations in the HMOX1 and UGT1A1 genes are not likely to protect from progression of liver disease in patients with chronic hepatitis C. No differences were found in the frequencies of each particular allele of both genes, between HCV patients and a control group (p > 0.05). Furthermore, no association was detected (p > 0.05) between either the HMOX1 or the UGT1A1 promoter variants and the individual histological stages of liver disease in the HCV positive patients. Finally, no differences in the HMOX1 and UGT1A1 genotype prevalence rates were found between pre-cirrhotic and cirrhotic patients (p > 0.05). Based on our data, microsatellite variations in the HMOX1 and UGT1A1 genes are not likely to protect from progression of liver disease in patients with chronic hepatitis C. (en)
Title	No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C (en)
skos:prefLabel	No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C (en)
skos:notation	RIV/61383082:_____/11:0071!RIV12-MO0-61383082
http://linked.open...avai/riv/aktivita	I P V
http://linked.open...avai/riv/aktivity	I, P(NR9412), V
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Urbánek, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	ÚVN - VFN Praha
http://linked.open...dnocenehoVysledku	216110
http://linked.open...ai/riv/idVysledku	RIV/61383082:_____/11:0071
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Hemoxygenase; biliverdinreduktase (en)
http://linked.open.../riv/klicoveSlovo	Hemoxygenase biliverdinreduktase
http://linked.open...odStatuVydavatele	MX - Spojené státy mexické
http://linked.open...ontrolniKodProRIV	[42A41B375580]
http://linked.open...i/riv/nazevZdroje	Annals of hepatology
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of heme oxygenase in the pathogenesis of hepatocelular injury in chronic HCV infection
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	10
http://linked.open...iv/tvurceVysledku	Dušek, L. Urbánek, Petr Muchová, L. Bruha, R. Hrabal, P. Kaspříková, N. Leníček, M. Subhanová, I. Vítek, L.
issn	1665-2681
number of pages	7 (xsd:int)

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