About: Volume of the amygdala is reduced in patients with narcolepsy

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About: Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Based on the clinical observation that patients suffering from narcolepsy with cataplexy (NC) have cataplectic attacks when they experience positive emotions, it is therefore hypothesised that the abnormal processing of external emotional input through the limbic system, or motor dysregulation induced by emotions, takes place during these episodes. To date, imaging studies have failed to reveal consistent brain abnormalities in NC patients. METHODS: Considering the discrepancies in reported structural or functional abnormalities of the hypothalamus, amygdala, and nucleus accumbens, we used the MRI volumetry to determine the volumes of the amygdala and nucleus accumbens in a group of eleven patients with NC (5 males and 6 females, mean age 41.7 years ± 17.7). Based on the clinical observation that patients suffering from narcolepsy with cataplexy (NC) have cataplectic attacks when they experience positive emotions, it is therefore hypothesised that the abnormal processing of external emotional input through the limbic system, or motor dysregulation induced by emotions, takes place during these episodes. To date, imaging studies have failed to reveal consistent brain abnormalities in NC patients. METHODS: Considering the discrepancies in reported structural or functional abnormalities of the hypothalamus, amygdala, and nucleus accumbens, we used the MRI volumetry to determine the volumes of the amygdala and nucleus accumbens in a group of eleven patients with NC (5 males and 6 females, mean age 41.7 years ± 17.7). (en)
Title	Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study (en)
skos:prefLabel	Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study (en)
skos:notation	RIV/61383082:_____/11:0062!RIV12-MO0-61383082
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(NR8931), P(NS10331), V
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hořínek, Daniel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	ÚVN - VFN Praha
http://linked.open...dnocenehoVysledku	239527
http://linked.open...ai/riv/idVysledku	RIV/61383082:_____/11:0062
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Narcolepsy; cataplexy; MRI volumetry; amygdala; nucleus accumbens (en)
http://linked.open.../riv/klicoveSlovo	Narcolepsy amygdala MRI volumetry cataplexy nucleus accumbens
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[4AA3092D71E4]
http://linked.open...i/riv/nazevZdroje	NeuroEndocrinology Letters
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...vavai/riv/projekt	Plasticity of deep structures of CNS in the course of life (in morphological and MRI view) in healthy persons and pathologic states The causes of cognitive deficit in internal carotid artery occlusion
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	35
http://linked.open...iv/tvurceVysledku	Hořínek, Daniel Brabec, J.
issn	0172-780X
number of pages	5 (xsd:int)

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