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  • In the industrial fermentation processes, most of the liquids are non-coalescent batches and few of them are coalescent. However, due to the limitations of most measurement methods, there is a lack of reliable data for predicting volumetric mass transfer coefficients (kLa) for non-coalescent batches under high dissipated energies. Our goal is to propose accurate kLa and power input (P) correlations for these conditions. Thus kLa was measured with the highly precise dynamic pressure method. Measurements were conducted in a two phase multiple-impeller fermenter with a non-coalescent and coalescent batch under a wide range of conditions. The classic correlation for kLa is based on P and superficial gas velocity, but we found that when impeller tip speed is switched with P it improved the closeness of the correlation for non-coalescent batches. The data aggregated from different impellers showed that the impeller power number is a reliable predictor of kLa for most impeller types. We confirmed that the ungassed P and gas superficial velocity is the most reliable term for prediction of P. We believe that these correlations can be used for scale-up purposes in the accurate design of industrial fermenters or their intensification under a wide range of operational conditions.
  • In the industrial fermentation processes, most of the liquids are non-coalescent batches and few of them are coalescent. However, due to the limitations of most measurement methods, there is a lack of reliable data for predicting volumetric mass transfer coefficients (kLa) for non-coalescent batches under high dissipated energies. Our goal is to propose accurate kLa and power input (P) correlations for these conditions. Thus kLa was measured with the highly precise dynamic pressure method. Measurements were conducted in a two phase multiple-impeller fermenter with a non-coalescent and coalescent batch under a wide range of conditions. The classic correlation for kLa is based on P and superficial gas velocity, but we found that when impeller tip speed is switched with P it improved the closeness of the correlation for non-coalescent batches. The data aggregated from different impellers showed that the impeller power number is a reliable predictor of kLa for most impeller types. We confirmed that the ungassed P and gas superficial velocity is the most reliable term for prediction of P. We believe that these correlations can be used for scale-up purposes in the accurate design of industrial fermenters or their intensification under a wide range of operational conditions. (en)
Title
  • Prediction of power consumption and mass transfer in mechanically agitated fermenters, physical interpretation of experimental data.
  • Prediction of power consumption and mass transfer in mechanically agitated fermenters, physical interpretation of experimental data. (en)
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  • Prediction of power consumption and mass transfer in mechanically agitated fermenters, physical interpretation of experimental data.
  • Prediction of power consumption and mass transfer in mechanically agitated fermenters, physical interpretation of experimental data. (en)
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  • RIV/60461373:22340/14:43897954!RIV15-MSM-22340___
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  • 38761
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  • RIV/60461373:22340/14:43897954
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  • multiple-impeller; gas-liquid; coalescence; volumetric mass transfer coefficients; power input (en)
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  • [86B476864335]
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  • Praha
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  • Praha
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  • Proceedings of the 21st International Congress of Chemical and Process Engineering CHISA 2014
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  • Moucha, Tomáš
  • Labík, Libor
  • Krejčí, Anna
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  • Česká společnost chemického inženýrství
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  • 978-80-02-02555-9
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  • 22340
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