About: Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances

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About: Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The goal was to prepare composite lipide/Fe3O4/SiO2 nanoparticles from hollow porous silica shell nanoparticles (100-300 nm) prepared by soft template emulsion method, magnetic iron oxide nanoparticles (5-20 nm) prepared by co-precipitation method and lipide nanoparticles (20-40 nm) prepared by high pressure homogenization.. First composite Fe3O4/SiO2 nanoparticles were prepared by coating silica with monolayer of iron oxide. The composite particles was then loaded with active substance and coated with layer of lipide nanoparticles to form oclusive lipide barrier which block diffusion in and out of the particles, thus preserving the active substance inside. The particles were cahracterised using transmission electron microscopy, dynamic light scattering and electrophoretic light scattering. The release mechanism is triggered by alternating radiofrequency field which heats up the magnetic iron oxide particles and melts the lipidic barrier which opens pores and the active substance diffuses into the environment. Release kinetics of the active substance were measured using UV-VIS spectrophotometer. The goal was to prepare composite lipide/Fe3O4/SiO2 nanoparticles from hollow porous silica shell nanoparticles (100-300 nm) prepared by soft template emulsion method, magnetic iron oxide nanoparticles (5-20 nm) prepared by co-precipitation method and lipide nanoparticles (20-40 nm) prepared by high pressure homogenization.. First composite Fe3O4/SiO2 nanoparticles were prepared by coating silica with monolayer of iron oxide. The composite particles was then loaded with active substance and coated with layer of lipide nanoparticles to form oclusive lipide barrier which block diffusion in and out of the particles, thus preserving the active substance inside. The particles were cahracterised using transmission electron microscopy, dynamic light scattering and electrophoretic light scattering. The release mechanism is triggered by alternating radiofrequency field which heats up the magnetic iron oxide particles and melts the lipidic barrier which opens pores and the active substance diffuses into the environment. Release kinetics of the active substance were measured using UV-VIS spectrophotometer. (en)
Title	Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances (en)
skos:prefLabel	Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances (en)
skos:notation	RIV/60461373:22340/14:43897688!RIV15-MSM-22340___
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Vidlářová, Lucie Štěpánek, František Kovačík, Pavel Šoltys, Marek
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
http://linked.open...dnocenehoVysledku	48967
http://linked.open...ai/riv/idVysledku	RIV/60461373:22340/14:43897688
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	controlled release; lipide/fe3o4/sio2 nanoparticles; porous; hollow; composite (en)
http://linked.open.../riv/klicoveSlovo	composite hollow porous lipide/fe3o4/sio2 nanoparticles controlled release
http://linked.open...ontrolniKodProRIV	[4128A895DFD4]
http://linked.open...v/mistoKonaniAkce	Tatranské Matliare
http://linked.open...i/riv/mistoVydani	Bratislava
http://linked.open...i/riv/nazevZdroje	Proceedings of the 41st International Conference of Slovak Society of Chemical Engineering
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Štěpánek, František Kovačík, Pavel Šoltys, Marek Vidlářová, Lucie
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2014-05-26 (xsd:date)
number of pages	10 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Slovak Society of Chemical Engineering
https://schema.org/isbn	978-80-89475-13-1
http://localhost/t...ganizacniJednotka	22340

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