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Description
  • In this paper, the application of an adaptive algorithm for control of fed-batch bioprocess capable of coping with time-variant process properties in the presence of uncertainties is introduced. The proposed adaptive controller uses Maršík?s heuristic algorithm for adaptation based on control error oscillation rate criterion without the need of a mathematical model of the controlled process or any special test signals. The intended application of the resulting controller was off-gas CO2 concentration control in fed-batch yeast cultivations where the set point has the form of a time-varying concentration profile. The controller has been tested in a series of experimental fed-batch cultivations with D7 Saccharomyces cerevisiae strain, a UV mutant suitable for ergosterol production, in 7-litre laboratory bioreactor. Obtained results demonstrate good properties of this adaptive controller that can be used without the need for a tedious parameter identification of the complex bioprocess.
  • In this paper, the application of an adaptive algorithm for control of fed-batch bioprocess capable of coping with time-variant process properties in the presence of uncertainties is introduced. The proposed adaptive controller uses Maršík?s heuristic algorithm for adaptation based on control error oscillation rate criterion without the need of a mathematical model of the controlled process or any special test signals. The intended application of the resulting controller was off-gas CO2 concentration control in fed-batch yeast cultivations where the set point has the form of a time-varying concentration profile. The controller has been tested in a series of experimental fed-batch cultivations with D7 Saccharomyces cerevisiae strain, a UV mutant suitable for ergosterol production, in 7-litre laboratory bioreactor. Obtained results demonstrate good properties of this adaptive controller that can be used without the need for a tedious parameter identification of the complex bioprocess. (en)
Title
  • Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations
  • Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations (en)
skos:prefLabel
  • Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations
  • Adaptive Control of Saccharomyces cerevisiae Yeasts Fed-Batch Cultivations (en)
skos:notation
  • RIV/60461373:22340/13:43895134!RIV14-MSM-22340___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6046137306)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 59479
http://linked.open...ai/riv/idVysledku
  • RIV/60461373:22340/13:43895134
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Saccharomyces cerevisiae; baker's yeast; fed-batch cultivation; identification-free; adaptive control (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • HR - Chorvatská republika
http://linked.open...ontrolniKodProRIV
  • [7F3F775E0595]
http://linked.open...i/riv/nazevZdroje
  • Chemical and Biochemical Engineering Quarterly
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Hrnčiřík, Pavel
  • Mareš, Jan
  • Náhlík, Jan
  • Vovsík, Jaroslav
http://linked.open...ain/vavai/riv/wos
  • 000326058300007
http://linked.open...n/vavai/riv/zamer
issn
  • 0352-9568
number of pages
http://localhost/t...ganizacniJednotka
  • 22340
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