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Description
| - The early liposome-based medicaments employed the idea of slow release and hence the medicinal effect is prolonged. However, the liposomes have more potential. Depending on its composition, the phospholipid bilayer undergoes a phase transition that makes the membrane much more permeable. The membrane is solid-like and little permeable at lower temperatures. At a phase transition temperature, the bilayer melts to liquid-like structure characterized by more mobile phospholipid molecules, which causes the membrane to be more permeable and less rigid. The phase change temperature is characteristic to the phospholipid bilayer; it depends on a length and a saturation of fatty acids chains and it is different for a particular polar head type. An existence of the phase change makes the release from liposomes controllable by temperature.
- The early liposome-based medicaments employed the idea of slow release and hence the medicinal effect is prolonged. However, the liposomes have more potential. Depending on its composition, the phospholipid bilayer undergoes a phase transition that makes the membrane much more permeable. The membrane is solid-like and little permeable at lower temperatures. At a phase transition temperature, the bilayer melts to liquid-like structure characterized by more mobile phospholipid molecules, which causes the membrane to be more permeable and less rigid. The phase change temperature is characteristic to the phospholipid bilayer; it depends on a length and a saturation of fatty acids chains and it is different for a particular polar head type. An existence of the phase change makes the release from liposomes controllable by temperature. (en)
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Title
| - Investigation of temperature-dependent release kinetics from free and immobilized liposomes
- Investigation of temperature-dependent release kinetics from free and immobilized liposomes (en)
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skos:prefLabel
| - Investigation of temperature-dependent release kinetics from free and immobilized liposomes
- Investigation of temperature-dependent release kinetics from free and immobilized liposomes (en)
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skos:notation
| - RIV/60461373:22340/12:43893623!RIV13-MSM-22340___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22340/12:43893623
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - immobilized liposomes; kinetics; release; temperature-dependent (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Štěpánek, František
- Ullrich, Martin
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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number of pages
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http://purl.org/ne...btex#hasPublisher
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https://schema.org/isbn
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http://localhost/t...ganizacniJednotka
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