About: Effects of Convective Flow On Chemical Signaling in Cellular Systems

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this contribution, we will introduce mathematical models of the key processes in such multicellular systems: the growth factor and protease diffusion and convection transport in an extracellular matrix and their release into the matrix, the ligand-receptor binding and simplified intracellular cascades leading to the ligand synthesis. Due to the consideration of the convective transport, these mathematical models significantly extend our insight into the chemical signaling in cellular systems based previously on reaction-diffusion equations. We believe that such mathematical models can be helpful for understanding developmental processes (vascular system formation) and also for understanding of cell motility in tissues (tissue injury, migration of cancer cells). Introductory results will be presented in this contribution. In this contribution, we will introduce mathematical models of the key processes in such multicellular systems: the growth factor and protease diffusion and convection transport in an extracellular matrix and their release into the matrix, the ligand-receptor binding and simplified intracellular cascades leading to the ligand synthesis. Due to the consideration of the convective transport, these mathematical models significantly extend our insight into the chemical signaling in cellular systems based previously on reaction-diffusion equations. We believe that such mathematical models can be helpful for understanding developmental processes (vascular system formation) and also for understanding of cell motility in tissues (tissue injury, migration of cancer cells). Introductory results will be presented in this contribution. (en)
Title	Effects of Convective Flow On Chemical Signaling in Cellular Systems Effects of Convective Flow On Chemical Signaling in Cellular Systems (en)
skos:prefLabel	Effects of Convective Flow On Chemical Signaling in Cellular Systems Effects of Convective Flow On Chemical Signaling in Cellular Systems (en)
skos:notation	RIV/60461373:22340/10:00023540!RIV11-MSM-22340___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ME10036), Z(MSM6046137306)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Přibyl, Michal Schreiber, Igor
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
http://linked.open...dnocenehoVysledku	256294
http://linked.open...ai/riv/idVysledku	RIV/60461373:22340/10:00023540
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	convective flow; cellular signaling; EGFR; mathematical modeling (en)
http://linked.open.../riv/klicoveSlovo	EGFR cellular signaling mathematical modeling convective flow
http://linked.open...ontrolniKodProRIV	[0DEB91E6D0EA]
http://linked.open...v/mistoKonaniAkce	Salt Lake CIty
http://linked.open...i/riv/mistoVydani	Nashville
http://linked.open...i/riv/nazevZdroje	2010 AIChE Annual Meeting Conference Proceedings
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Effects of convective transport on chemical signal propagation in living tissues
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Schreiber, Igor Přibyl, Michal
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2010-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Reakčně-transportní chemicko-inženýrské systémy a jejich dynamické chování, modelování a řízení chemických a biotechnologických procesů
number of pages	10 (xsd:int)
http://purl.org/ne...btex#hasPublisher	American Institute of Chemical Engineers
https://schema.org/isbn	978-0-8169-1065-6
http://localhost/t...ganizacniJednotka	22340

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