About: Study on surface properties of PDMS microfluidic chips treated with albumin

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Electrokinetic properties and morphology of PDMS microfluidic chips intended for bioassays are studied. The chips are fabricated by a casting method followed by polymerization bonding. Microchannels are coated with 1% solution of bovine serum albumin (BSA) in Tris buffer. Albumin passively adsorbs on the PDMS surface. Electrokinetic characteristics (electro-osmotic velocity, electro-osmotic mobility, and zeta potential) of the coated PDMS channels are experimentally determined as functions of the electric field strength and the characteristic electrolyte concentration. Atomic force microscopy (AFM) analysis of the surface reveals a %22peak and ridge%22 structure of the protein layer and an imperfect substrate coating. On the basis of the AFM observation, several topologies of the BSA-PDMS surface are proposed. A nonslip mathematical model of the electro-osmotic flow is then numerically analyzed. It is found that the electrokinetic characteristics computed for a channel with the homogeneous distr Electrokinetic properties and morphology of PDMS microfluidic chips intended for bioassays are studied. The chips are fabricated by a casting method followed by polymerization bonding. Microchannels are coated with 1% solution of bovine serum albumin (BSA) in Tris buffer. Albumin passively adsorbs on the PDMS surface. Electrokinetic characteristics (electro-osmotic velocity, electro-osmotic mobility, and zeta potential) of the coated PDMS channels are experimentally determined as functions of the electric field strength and the characteristic electrolyte concentration. Atomic force microscopy (AFM) analysis of the surface reveals a %22peak and ridge%22 structure of the protein layer and an imperfect substrate coating. On the basis of the AFM observation, several topologies of the BSA-PDMS surface are proposed. A nonslip mathematical model of the electro-osmotic flow is then numerically analyzed. It is found that the electrokinetic characteristics computed for a channel with the homogeneous distr (en)
Title	Study on surface properties of PDMS microfluidic chips treated with albumin Study on surface properties of PDMS microfluidic chips treated with albumin (en)
skos:prefLabel	Study on surface properties of PDMS microfluidic chips treated with albumin Study on surface properties of PDMS microfluidic chips treated with albumin (en)
skos:notation	RIV/60461373:22340/09:00021956!RIV10-MSM-22340___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KAN208240651), Z(MSM6046137306)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Slouka, Zdeněk Přibyl, Michal Šnita, Dalimil Červenka, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
http://linked.open...dnocenehoVysledku	344563
http://linked.open...ai/riv/idVysledku	RIV/60461373:22340/09:00021956
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	bioMEMS; electrolytes; electrophoresis; microfluidics; molecular biophysics; osmosis; polymerisation; polymers; proteins (en)
http://linked.open.../riv/klicoveSlovo	polymers electrolytes electrophoresis microfluidics proteins bioMEMS molecular biophysics polymerisation osmosis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[44D1B16D28A5]
http://linked.open...i/riv/nazevZdroje	Biomicrofluidics
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of interactions of biological macromolecules and nanolayers with a view to research of polymer microfluidic biosensors and therapeutic nanoparticles
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	3
http://linked.open...iv/tvurceVysledku	Slouka, Zdeněk Šnita, Dalimil Nebyla, Marek Přibyl, Michal Schrott, Walter Červenka, Petr Ston, Jiří
http://linked.open...ain/vavai/riv/wos	000273217500001
http://linked.open...n/vavai/riv/zamer	Reakčně-transportní chemicko-inženýrské systémy a jejich dynamické chování, modelování a řízení chemických a biotechnologických procesů
issn	1932-1058
number of pages	15 (xsd:int)
http://localhost/t...ganizacniJednotka	22340

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