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  • Sequential cationic oligopeptides of the different length of peptide chain, H-(L-lysyl-L-alanyl-L-alanine)n-OMe, (KAA)n, n = 1, 2 and 3, were synthesized and their solution conformations were investigated over a range of temperatures using a combination of spectroscopic techniques with emphasis to vibrational (VCD) and electronic (ECD) circular dichroism spectroscopies. Singular value decomposition (SVD) method of factor analysis (FA) was applied to help understand the thermal stability and thermally induced conformational changes.
  • Sequential cationic oligopeptides of the different length of peptide chain, H-(L-lysyl-L-alanyl-L-alanine)n-OMe, (KAA)n, n = 1, 2 and 3, were synthesized and their solution conformations were investigated over a range of temperatures using a combination of spectroscopic techniques with emphasis to vibrational (VCD) and electronic (ECD) circular dichroism spectroscopies. Singular value decomposition (SVD) method of factor analysis (FA) was applied to help understand the thermal stability and thermally induced conformational changes. (en)
Title
  • Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution
  • Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution (en)
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  • Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution
  • Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution (en)
skos:notation
  • RIV/60461373:22340/08:00022855!RIV10-GA0-22340___
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  • P(GP203/06/P371)
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  • 361023
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  • RIV/60461373:22340/08:00022855
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  • cationic oligopeptides; circular dichroism; IR; conformation; stability (en)
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  • [37AC588A50E3]
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  • Helsinki, Finsko
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  • Finsko
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  • Peptides 2008 - Chemistry of Peptides in Life Science, Technology and Medicine
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  • Hlaváček, J.
  • Urbanová, Marie
  • Setnička, Vladimír
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number of pages
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  • The Finnish Peptide Society
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  • 978-952-92-5198-8
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  • 22340
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