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Description
| - A mathematical model of an enzymatic separating microreactor with the electro-osmotic control of reaction component transport rates is analysed. The micro-reactor is considered in a form of a thin channel filled with a gel containing an immobilised enzyme and an adsorbent where the enzyme reaction, the molecular diffusion, the electro-osmotic flux and the adsorption take place. The substrate inhibited enzyme reaction splitting a non-ionic substrate to two non-ionic products is considered. The reactor operates in a periodic regime, when the channel entry is exposed to the periodic substrate concentration pulses. A chromatographic separation of reaction components, therefore, proceeds in the channel. Effects of principal operational parameters of the reactor system - the reaction channel length, the electric current density, the substrate inlet concentration, the rate of adsorption, and the enzyme activity - on resolution of the products at reactor outlet are analysed. The existence of optimum parameter
- A mathematical model of an enzymatic separating microreactor with the electro-osmotic control of reaction component transport rates is analysed. The micro-reactor is considered in a form of a thin channel filled with a gel containing an immobilised enzyme and an adsorbent where the enzyme reaction, the molecular diffusion, the electro-osmotic flux and the adsorption take place. The substrate inhibited enzyme reaction splitting a non-ionic substrate to two non-ionic products is considered. The reactor operates in a periodic regime, when the channel entry is exposed to the periodic substrate concentration pulses. A chromatographic separation of reaction components, therefore, proceeds in the channel. Effects of principal operational parameters of the reactor system - the reaction channel length, the electric current density, the substrate inlet concentration, the rate of adsorption, and the enzyme activity - on resolution of the products at reactor outlet are analysed. The existence of optimum parameter (en)
- Je studován matematický model enzymového separačního mikroreaktoru využívajícího elektroosmotický transport reakčních složek. Reaktor je tvořen kanálkem vyplněným gelem s imobilizovaným enzymem a rozptýlenými mikročásticemi sorbentu. Substrát se enzymovou reakcí štěpí na dva produkty s různou silou sorpce. Reaktor je provozován v periodickém režimu a dochází ke střídání reakční a separační periody. Je vykonána optimalizace geometrických a provozních parametrů systému v závislosti na základních provozních parametrech. (cs)
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Title
| - Modelling and optimization of enzymatic separating microreactor
- Modelling and optimization of enzymatic separating microreactor (en)
- Modelování a optimalizace enzymového separačního mikroreaktoru. (cs)
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skos:prefLabel
| - Modelling and optimization of enzymatic separating microreactor
- Modelling and optimization of enzymatic separating microreactor (en)
- Modelování a optimalizace enzymového separačního mikroreaktoru. (cs)
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skos:notation
| - RIV/60461373:22340/05:00014598!RIV06-GA0-22340___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA104/01/1319), Z(MSM6046137306)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22340/05:00014598
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - microreactor; reaction and separation; adsorption; enzyme reaction; electroosmosis; optimization (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Bioprocess and Biosystems Engineering
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hasal, Pavel
- Tměj, Filip
- Limbergová, Zdena
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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