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  • A mathematical model of an enzymatic separating microreactor with the electro-osmotic control of reaction component transport rates is analysed. The micro-reactor is considered in a form of a thin channel filled with a gel containing an immobilised enzyme and an adsorbent where the enzyme reaction, the molecular diffusion, the electro-osmotic flux and the adsorption take place. The substrate inhibited enzyme reaction splitting a non-ionic substrate to two non-ionic products is considered. The reactor operates in a periodic regime, when the channel entry is exposed to the periodic substrate concentration pulses. A chromatographic separation of reaction components, therefore, proceeds in the channel. Effects of principal operational parameters of the reactor system - the reaction channel length, the electric current density, the substrate inlet concentration, the rate of adsorption, and the enzyme activity - on resolution of the products at reactor outlet are analysed. The existence of optimum parameter
  • A mathematical model of an enzymatic separating microreactor with the electro-osmotic control of reaction component transport rates is analysed. The micro-reactor is considered in a form of a thin channel filled with a gel containing an immobilised enzyme and an adsorbent where the enzyme reaction, the molecular diffusion, the electro-osmotic flux and the adsorption take place. The substrate inhibited enzyme reaction splitting a non-ionic substrate to two non-ionic products is considered. The reactor operates in a periodic regime, when the channel entry is exposed to the periodic substrate concentration pulses. A chromatographic separation of reaction components, therefore, proceeds in the channel. Effects of principal operational parameters of the reactor system - the reaction channel length, the electric current density, the substrate inlet concentration, the rate of adsorption, and the enzyme activity - on resolution of the products at reactor outlet are analysed. The existence of optimum parameter (en)
  • Je studován matematický model enzymového separačního mikroreaktoru využívajícího elektroosmotický transport reakčních složek. Reaktor je tvořen kanálkem vyplněným gelem s imobilizovaným enzymem a rozptýlenými mikročásticemi sorbentu. Substrát se enzymovou reakcí štěpí na dva produkty s různou silou sorpce. Reaktor je provozován v periodickém režimu a dochází ke střídání reakční a separační periody. Je vykonána optimalizace geometrických a provozních parametrů systému v závislosti na základních provozních parametrech. (cs)
Title
  • Modelling and optimization of enzymatic separating microreactor
  • Modelling and optimization of enzymatic separating microreactor (en)
  • Modelování a optimalizace enzymového separačního mikroreaktoru. (cs)
skos:prefLabel
  • Modelling and optimization of enzymatic separating microreactor
  • Modelling and optimization of enzymatic separating microreactor (en)
  • Modelování a optimalizace enzymového separačního mikroreaktoru. (cs)
skos:notation
  • RIV/60461373:22340/05:00014598!RIV06-GA0-22340___
http://linked.open.../vavai/riv/strany
  • 123-130
http://linked.open...avai/riv/aktivita
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  • P(GA104/01/1319), Z(MSM6046137306)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 530623
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  • RIV/60461373:22340/05:00014598
http://linked.open...riv/jazykVysledku
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  • microreactor; reaction and separation; adsorption; enzyme reaction; electroosmosis; optimization (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [30B89F23AA57]
http://linked.open...i/riv/nazevZdroje
  • Bioprocess and Biosystems Engineering
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Hasal, Pavel
  • Tměj, Filip
  • Limbergová, Zdena
http://linked.open...n/vavai/riv/zamer
issn
  • 1615-7591
number of pages
http://localhost/t...ganizacniJednotka
  • 22340
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