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| rdf:type
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| Description
| - Purpose: Since the number of cancer patients treated by proton irradiation has increased in the last few years, it seems appropriate to study dose-dependent effects of proton irradiation on mammalian tissues in more detail. Materials and methods: Tissue samples of normal skin of mouse and swine, of a human tumour model xenograph, and of normal skin and a skin tumour ( basal cell carcinoma) of a human patient of about 1 mm thickness were irradiated by 24MeV protons ( uniform delivered doses of 1, 7 and 50 Gy: skin of mouse and a human tumour model xenograph, and 0.5, 5 and 50 Gy: swine and human skin). Raman spectra of non-irradiated and irradiated samples were recorded and analysed.Results: Amide I, P=O and C-O bond vibrations and aromatics were sensitive to the proton irradiation dose. In the C-H stretching region, the irradiation-mediated change of Raman spectra was significant only in the case of the skin tumour.Conclusions: It has been shown that Raman spectroscopy is suited to assess the radiatio
- Purpose: Since the number of cancer patients treated by proton irradiation has increased in the last few years, it seems appropriate to study dose-dependent effects of proton irradiation on mammalian tissues in more detail. Materials and methods: Tissue samples of normal skin of mouse and swine, of a human tumour model xenograph, and of normal skin and a skin tumour ( basal cell carcinoma) of a human patient of about 1 mm thickness were irradiated by 24MeV protons ( uniform delivered doses of 1, 7 and 50 Gy: skin of mouse and a human tumour model xenograph, and 0.5, 5 and 50 Gy: swine and human skin). Raman spectra of non-irradiated and irradiated samples were recorded and analysed.Results: Amide I, P=O and C-O bond vibrations and aromatics were sensitive to the proton irradiation dose. In the C-H stretching region, the irradiation-mediated change of Raman spectra was significant only in the case of the skin tumour.Conclusions: It has been shown that Raman spectroscopy is suited to assess the radiatio (en)
- Účinnost různých dávek záření urychlených protonů na efektivní opracovaní nemocných tkání byla sledovaná Ramanovou spektroskopií. Tkáňové vzorky normální myší, prasečí a lidské kůže byli porovnané se vzorkama nemocných tkáni basal cell karcinomu, adenokarcinomu před a po ozářeni 24 MeV urychlenými protony při 0,5; 1; 5; 7; 50 Gy. Změny v biologickém materiálu vyvolané ozářením urychlenými protony byli prostudovány a diskutovány. (cs)
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| Title
| - Raman spektroskopické studium vlivu protonové radiace na vzorky tkání (cs)
- Raman spectroscopy of tissue samples irradiated by protons
- Raman spectroscopy of tissue samples irradiated by protons (en)
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| skos:prefLabel
| - Raman spektroskopické studium vlivu protonové radiace na vzorky tkání (cs)
- Raman spectroscopy of tissue samples irradiated by protons
- Raman spectroscopy of tissue samples irradiated by protons (en)
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| skos:notation
| - RIV/60461373:22340/04:00013202!RIV/2005/GA0/223405/N
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GV301/98/K042), Z(MSM 223400008)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22340/04:00013202
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Raman spectroscopy;irradiated by protons;tumour (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - International Journal of Radiation Biology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Synytsya, Alla
- Obstová, I.
- Alexa, Petr
- Volka, Karel
- Loewe, M.
- Wuerkner, M.
- Froschauer, S.
- Gerlach, R.
- Moosburger, M.
- Quicken, P.
- Sosna, B.
- Besserer, J.
- Boer, J.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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