About: DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This work is focused on development of a microdevice for an immunoassay performed on asolid phase. Our efforts cover both the mathematical modeling of realistic microsystems andthe development of experimental procedures for construction of such microdevices.Description of microdevices for the ELISA applications is rarely reported in theliterature. They usually consist of either a layer of microparticles with immobilized antigen orwith an antigen bound on walls of microchannels. None of the reported applications has beencommercially used yet. In addition to high costs, these microdevices have still manydisadvantages such as difficult manipulation with microparticles, low concentration ofantibody at walls with the immobilized antigen, irregularity in the layer of the immobilizedantigen etc.We propose a system that should minimize these disadvantages. The central part ofthis microdevice contains a porous material. Pores of the material are permeable for smallmolecules and ions. Larger molecules (e.g. pro This work is focused on development of a microdevice for an immunoassay performed on asolid phase. Our efforts cover both the mathematical modeling of realistic microsystems andthe development of experimental procedures for construction of such microdevices.Description of microdevices for the ELISA applications is rarely reported in theliterature. They usually consist of either a layer of microparticles with immobilized antigen orwith an antigen bound on walls of microchannels. None of the reported applications has beencommercially used yet. In addition to high costs, these microdevices have still manydisadvantages such as difficult manipulation with microparticles, low concentration ofantibody at walls with the immobilized antigen, irregularity in the layer of the immobilizedantigen etc.We propose a system that should minimize these disadvantages. The central part ofthis microdevice contains a porous material. Pores of the material are permeable for smallmolecules and ions. Larger molecules (e.g. pro (en) Práce je zaměřena na vývoj mikrozařízení pro imunoanalýzu na pevném nosiči. Naše snahy zahrnují matematické modelování realistických mikrosystémů a také vývoj experimentálních procedur pro konstrukci takových zařízení. Byl navržen model mikrozařízení pro imunoanalýzu, který umožňuje minimalizovat spotřebu drahých reaktantů a zároveň zkoncentrování roztoku u povrchu s vázanými aktivními molekulami. (cs)
Title	Vývoj ELISA systému na mikročipové bázi (cs) DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM (en)
skos:prefLabel	Vývoj ELISA systému na mikročipové bázi (cs) DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM (en)
skos:notation	RIV/60461373:22340/04:00013195!RIV/2005/GA0/223405/N
http://linked.open.../vavai/riv/strany	099 (1-8)
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA104/02/0339), Z(MSM 223400007)
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Hasal, Pavel Marek, Miloš Přibyl, Michal Šnita, Dalimil
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
http://linked.open...dnocenehoVysledku	560202
http://linked.open...ai/riv/idVysledku	RIV/60461373:22340/04:00013195
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Immunoassay;ELISA;mathematical modeling;microchip;Poisson equation;Antigen;antibody (en)
http://linked.open.../riv/klicoveSlovo	Immunoassay microchip Antigen ELISA antibody mathematical modeling Poisson equation
http://linked.open...ontrolniKodProRIV	[7CBFD66C3071]
http://linked.open...v/mistoKonaniAkce	Tatranské Matliare
http://linked.open...i/riv/mistoVydani	Bratislava
http://linked.open...i/riv/nazevZdroje	Proceeding of 31th International Conference of Chemical Engineering, Tatranské Matliare, Slovakia
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Nonstationary operation of microreactors
http://linked.open...UplatneniVysledku	2004
http://linked.open...iv/tvurceVysledku	Hasal, Pavel Šnita, Dalimil Přibyl, Michal Marek, Miloš
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2004-05-24 (xsd:date)
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20223400007
number of pages	8 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Slovak Society of Chemical Engineering
https://schema.org/isbn	80-227-2052-6
http://localhost/t...ganizacniJednotka	22340

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