About: The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood.

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About: The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.academicjournals.org/article/article1410257161_Lisov%C3%A1%20et%20al.pdf
Description	The immunomodulatory effect of nine strains of Lactobacillus plantarum by stimulation of human peripheral blood mononuclear cells (hPBMCs) from healthy donors was investigated. The production of pro-inflammatory, anti-inflammatory and regulatory cytokines by mononuclear cells following exposure of live bacterial cells was measured using multiplex analysis Luminex. The stimulation and production of cytokine by hPBMCs was evaluated to be strain specific and dependent on the density of cells used for stimulation. A significant increase of IL-6 and IL-1beta secretion was demonstrated following stimulation of hPMBCs by high densities of lactobacilli (P { 0.05). By contrast, low density of lactobacilli strains increased the production of TNF-alfa (P { 0.05) in seven out of nine strains tested. The results have also shown the importance of testing probiotics with using multiplex methods that can help to explanation of the effectiveness/ineffectiveness of probiotics in the treatment and prevention of gastrointestinal diseases and allergies. The immunomodulatory effect of nine strains of Lactobacillus plantarum by stimulation of human peripheral blood mononuclear cells (hPBMCs) from healthy donors was investigated. The production of pro-inflammatory, anti-inflammatory and regulatory cytokines by mononuclear cells following exposure of live bacterial cells was measured using multiplex analysis Luminex. The stimulation and production of cytokine by hPBMCs was evaluated to be strain specific and dependent on the density of cells used for stimulation. A significant increase of IL-6 and IL-1beta secretion was demonstrated following stimulation of hPMBCs by high densities of lactobacilli (P { 0.05). By contrast, low density of lactobacilli strains increased the production of TNF-alfa (P { 0.05) in seven out of nine strains tested. The results have also shown the importance of testing probiotics with using multiplex methods that can help to explanation of the effectiveness/ineffectiveness of probiotics in the treatment and prevention of gastrointestinal diseases and allergies. (en)
Title	The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood. The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood. (en)
skos:prefLabel	The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood. The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood. (en)
skos:notation	RIV/60461373:22330/14:43898386!RIV15-MZE-22330___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(QJ1210376)
http://linked.open...iv/cisloPeriodika	19
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Čurda, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	20546
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/14:43898386
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cytokine; immunomodulation; Lactobacillus plantarum (en)
http://linked.open.../riv/klicoveSlovo	immunomodulation Lactobacillus plantarum cytokine
http://linked.open...odStatuVydavatele	NG - Nigerijská federativní republika
http://linked.open...ontrolniKodProRIV	[F736F60EEAF3]
http://linked.open...i/riv/nazevZdroje	African Journal of Microbiology Research
http://linked.open...in/vavai/riv/obor	GM
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Colostrum as a source of new primary products in food and food supplements characterized by improved dietary properties and high content of natural biologically active substances.
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Kunová, Gabriela Šalaková, Alexandra Kolesár, Libor Lisová, Ivana Čurda, Ladislav Bártová, Jiřina
issn	1996-0808
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.5897/AJMR2014.6744
http://localhost/t...ganizacniJednotka	22330

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