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  • This work is focused on characterization of plasma treated and consequently etched and grafted biocompatible polymer poly(l-lactide acid) (PLLA). The interaction of biodegradable polymers with cold plasma is of a great importance in a tissue engineering and surface science. Cold plasma exposure, grafting with gold nanoparticles and etching processes were successfully applied to biopolymer substrate. A method for biopolymer nanostructuring as combination of cold plasma treatment and Au nanoparticle grafting for biocompatibility improvement is introduced. Surface roughness, morphology and surface chemistry was determined. The plasma modification leads to significant increase in surface roughness of PLLA and appearance of sharp spikes and ridges on the PLLA surface. Modification by grafting and etching leads to significant changes in PLLA surface morphology and chemistry. The surface ablation of PLLA has been proved to be significant. In etching of plasma-modified PLLA, methanol proves to be stronger etching agent than water. The grafting of PLLA with gold nanoparticles improved mouse embryonic fibroblasts (NIH 3T3) adhesion and proliferation significantly.
  • This work is focused on characterization of plasma treated and consequently etched and grafted biocompatible polymer poly(l-lactide acid) (PLLA). The interaction of biodegradable polymers with cold plasma is of a great importance in a tissue engineering and surface science. Cold plasma exposure, grafting with gold nanoparticles and etching processes were successfully applied to biopolymer substrate. A method for biopolymer nanostructuring as combination of cold plasma treatment and Au nanoparticle grafting for biocompatibility improvement is introduced. Surface roughness, morphology and surface chemistry was determined. The plasma modification leads to significant increase in surface roughness of PLLA and appearance of sharp spikes and ridges on the PLLA surface. Modification by grafting and etching leads to significant changes in PLLA surface morphology and chemistry. The surface ablation of PLLA has been proved to be significant. In etching of plasma-modified PLLA, methanol proves to be stronger etching agent than water. The grafting of PLLA with gold nanoparticles improved mouse embryonic fibroblasts (NIH 3T3) adhesion and proliferation significantly. (en)
Title
  • Poly-L-lactic acid modified by etching and grafting with gold nanoparticles
  • Poly-L-lactic acid modified by etching and grafting with gold nanoparticles (en)
skos:prefLabel
  • Poly-L-lactic acid modified by etching and grafting with gold nanoparticles
  • Poly-L-lactic acid modified by etching and grafting with gold nanoparticles (en)
skos:notation
  • RIV/60461373:22330/13:43895729!RIV14-GA0-22330___
http://linked.open...avai/riv/aktivita
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  • I, P(GBP108/12/G108)
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  • 17
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  • 97075
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  • RIV/60461373:22330/13:43895729
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  • Ar; biomaterial; tissue; cell-adhesion; surface modification; low-sensity polyethylene; Plasma-treated polymers (en)
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  • US - Spojené státy americké
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  • [D0FD011EF959]
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  • Journal of Materials Science
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  • 48
http://linked.open...iv/tvurceVysledku
  • Kolská, Zdeňka
  • Slepička, Petr
  • Švorčík, Václav
  • Ruml, Tomáš
  • Rimpelová, Silvie
  • Slepičková Kasálková, Nikola
  • Michaljaničová, Iva
http://linked.open...ain/vavai/riv/wos
  • 000321271100020
issn
  • 0022-2461
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s10853-013-7383-9
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  • 22330
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