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Description
  • Článek popisuje základní principy architektury retrovirových částic a přístupy k jejich studiu.
  • Článek popisuje základní principy architektury retrovirových částic a přístupy k jejich studiu. (cs)
  • This article describes basic principles of retroviral shell architecture and the approaches to its studies. Elucidation of the retrovirus particle structure, both in immature and mature forms, is essential for designing compounds that could block interactions at interfaces of viral proteins, which are critical for formation and stability of the particle. Detailed understanding of HIV structure could thus be a significant tool in the search for novel types of HIV inhibitors targeted on the assembly or maturation of this virus. (en)
Title
  • Structure of Retroviral Particles as a Tool for Designing HIV Inhibitors (en)
  • VYŘEŠENÍ STRUKTURY RETROVIROVÉ ČÁSTICE JAKO KLÍČ K INHIBICI HIV
  • VYŘEŠENÍ STRUKTURY RETROVIROVÉ ČÁSTICE JAKO KLÍČ K INHIBICI HIV (cs)
skos:prefLabel
  • Structure of Retroviral Particles as a Tool for Designing HIV Inhibitors (en)
  • VYŘEŠENÍ STRUKTURY RETROVIROVÉ ČÁSTICE JAKO KLÍČ K INHIBICI HIV
  • VYŘEŠENÍ STRUKTURY RETROVIROVÉ ČÁSTICE JAKO KLÍČ K INHIBICI HIV (cs)
skos:notation
  • RIV/60461373:22330/12:43894101!RIV13-MSM-22330___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LH12011)
http://linked.open...iv/cisloPeriodika
  • 10
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 179080
http://linked.open...ai/riv/idVysledku
  • RIV/60461373:22330/12:43894101
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cryo-electron microscopy; electron microscopy; M-PMV; HIV; retrovirus particle structure; assembly; retrovirus (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [69F2E106321D]
http://linked.open...i/riv/nazevZdroje
  • Chemické listy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 106
http://linked.open...iv/tvurceVysledku
  • Ruml, Tomáš
  • Ulbrich, Pavel
  • Voráčková, Irena
  • Füzik, Tibor
  • Píchalová, Růžena
http://linked.open...ain/vavai/riv/wos
  • 000310483000007
issn
  • 0009-2770
number of pages
http://localhost/t...ganizacniJednotka
  • 22330
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