About: Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Some time ago, we published an announcement that the azo group that closes model cyclic peptides is often reduced in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) in the presence of 2,5-dihydroxybenzoic acid (2,5-DHB) as the matrix. In this work, we demonstrate that these peptides are ionized in all DHB matrix isomers, although threshold ionization laser energies as well as the reduction ratios differ in each matrix. Using a NALDI plate, we confirmed that their reduction depends on the presence of DHB matrix and that the hydrogen atoms participating in the reaction come from the DHB matrix hydroxyl group. We show that the reduction ratio is affected by the overall covalent structure of the peptide, by the presence of a free carboxyl group in DHB matrix, by the mutual position of the hydroxyl and carboxyl groups, as well as the laser beam intensity. Based on these results, it can be concluded that the azo-group reduction in cyclic peptides is a very complex process and we are Some time ago, we published an announcement that the azo group that closes model cyclic peptides is often reduced in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) in the presence of 2,5-dihydroxybenzoic acid (2,5-DHB) as the matrix. In this work, we demonstrate that these peptides are ionized in all DHB matrix isomers, although threshold ionization laser energies as well as the reduction ratios differ in each matrix. Using a NALDI plate, we confirmed that their reduction depends on the presence of DHB matrix and that the hydrogen atoms participating in the reaction come from the DHB matrix hydroxyl group. We show that the reduction ratio is affected by the overall covalent structure of the peptide, by the presence of a free carboxyl group in DHB matrix, by the mutual position of the hydroxyl and carboxyl groups, as well as the laser beam intensity. Based on these results, it can be concluded that the azo-group reduction in cyclic peptides is a very complex process and we are (en)
Title	Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid (en)
skos:prefLabel	Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid Azo-group reduction during matrix-assisted laser desorption/ionization process in the presence of 2,5-dyhydroxybenzoic acid (en)
skos:notation	RIV/60461373:22330/10:00024237!RIV11-MSM-22330___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM6046137305)
http://linked.open...iv/cisloPeriodika	22
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Svoboda, Martin Kodíček, Milan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	248325
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/10:00024237
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Flight Mass-Spectrometry; Desorption Ionisation MALDI; TOF MS Analysis; p-Aminophenol; Isomers; Identification; Peptide; Model (en)
http://linked.open.../riv/klicoveSlovo	Peptide Isomers Desorption Ionisation MALDI Flight Mass-Spectrometry TOF MS Analysis Identification Model p-Aminophenol
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[349F4DEBBAF7]
http://linked.open...i/riv/nazevZdroje	Rapid Communications in Mass Spectrometry
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Kodíček, Milan Svoboda, Martin
http://linked.open...ain/vavai/riv/wos	000284023400017
http://linked.open...n/vavai/riv/zamer	Teoretické základy potravinářských a biochemických technologií
issn	0951-4198
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	22330

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 25 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software