About: Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Assembly of immature retroviral particles is mediated mainly by mutual interactions of capsid (CA) and nucleocapsid (NC) domains of Gag polyproteins and viral genomic RNA. We identified a ?basic domain? (NC16-23) at the N-terminus of Mason-Pfizer monkey virus (M-PMV) NC that contributes to the oligomerization of CA leading to the assembly of virus-like particles (VLP). Within the basic domain we identified a stretch of the three lysine residues K16, K18, and K20 crucial for the assembly. The basic region can be substituted by non-specific positively charged peptide. In summary, we report here the importance of basic residues at the N-terminus of M-PMV NC for the assembly of immature-like particles. Assembly of immature retroviral particles is mediated mainly by mutual interactions of capsid (CA) and nucleocapsid (NC) domains of Gag polyproteins and viral genomic RNA. We identified a ?basic domain? (NC16-23) at the N-terminus of Mason-Pfizer monkey virus (M-PMV) NC that contributes to the oligomerization of CA leading to the assembly of virus-like particles (VLP). Within the basic domain we identified a stretch of the three lysine residues K16, K18, and K20 crucial for the assembly. The basic region can be substituted by non-specific positively charged peptide. In summary, we report here the importance of basic residues at the N-terminus of M-PMV NC for the assembly of immature-like particles. (en)
Title	Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly (en)
skos:prefLabel	Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly Analysis of the N-terminus of nucleocapsid protein of Mason-Pfizer monkey virus: its role in the particle assembly (en)
skos:notation	RIV/60461373:22330/10:00024218!RIV11-MSM-22330___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ME 904)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Ruml, Tomáš
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	246503
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/10:00024218
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mason-Pfizer monkey virus; assembly; %22spacer-like%22 peptide (en)
http://linked.open.../riv/klicoveSlovo	assembly Mason-Pfizer monkey virus %22spacer-like%22 peptide
http://linked.open...ontrolniKodProRIV	[135515666F9E]
http://linked.open...v/mistoKonaniAkce	Prague, Czech Republic
http://linked.open...i/riv/mistoVydani	Bologna
http://linked.open...i/riv/nazevZdroje	Centennial Retrovirus Meeting
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20904
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Ruml, Tomáš Pichová, I. Bohmová, K. Hadravová, R. Rumlová, M. Štokrová, J.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2010-01-01 (xsd:date)
number of pages	5 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Editografica
https://schema.org/isbn	978-88-7587-586-2
http://localhost/t...ganizacniJednotka	22330

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software