About: ELISA estimation of S-equol in human body fluids

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Equol is a biologically active metabolite of isoflavonoid daidzein, which is the principle of food supplements designated for women in climacterium. The conversion from daidzein to equol is caused by the intestinal microflora. Therefore this microflora differs bethween individuals, the production of equol isn?t uniform. Equol is a chiral molecule. Always S-equol rise by the action of intestinal microflora in human body, R-equol was prepared only synthetically. S-equol acts as a weak agonist in estrogen receptors β and therefore is in many cases a good alternative to hormone replacement therapy. The object of this study was to optimize the competitive enzyme-liked immunosorbent assay (ELISA) method for the determination of equol in human body fluids using enantiometrically pure standards. Racemic equol conjugates coupled to bovine serum albumine at positions 4'-O- via carboxymethyl spacer were used as immunogens. Conjugates of the same hapten with ovalbumine were used for coating of the micr Equol is a biologically active metabolite of isoflavonoid daidzein, which is the principle of food supplements designated for women in climacterium. The conversion from daidzein to equol is caused by the intestinal microflora. Therefore this microflora differs bethween individuals, the production of equol isn?t uniform. Equol is a chiral molecule. Always S-equol rise by the action of intestinal microflora in human body, R-equol was prepared only synthetically. S-equol acts as a weak agonist in estrogen receptors β and therefore is in many cases a good alternative to hormone replacement therapy. The object of this study was to optimize the competitive enzyme-liked immunosorbent assay (ELISA) method for the determination of equol in human body fluids using enantiometrically pure standards. Racemic equol conjugates coupled to bovine serum albumine at positions 4'-O- via carboxymethyl spacer were used as immunogens. Conjugates of the same hapten with ovalbumine were used for coating of the micr (en)
Title	ELISA estimation of S-equol in human body fluids ELISA estimation of S-equol in human body fluids (en)
skos:prefLabel	ELISA estimation of S-equol in human body fluids ELISA estimation of S-equol in human body fluids (en)
skos:notation	RIV/60461373:22330/10:00024177!RIV11-GA0-22330___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA303/08/0958), Z(MSM6046137305)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Lanková, Petra Sosvorová, Lucie Lapčík, Oldřich
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	256928
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/10:00024177
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	S-equol; menopause; ELISA (en)
http://linked.open.../riv/klicoveSlovo	menopause S-equol ELISA
http://linked.open...ontrolniKodProRIV	[73927175725C]
http://linked.open...v/mistoKonaniAkce	Montpellier, Francie
http://linked.open...i/riv/mistoVydani	Montpellier
http://linked.open...i/riv/nazevZdroje	Polyphenols Communications 2010
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Phytoestrogens as an Alternative to Hormone Replacement Therapy - An Efficiency and Safety Study
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Bičíková, Marie Lapčík, Oldřich Lanková, Petra Sosvorová, Lucie Al-Maharik, N.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2010-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Teoretické základy potravinářských a biochemických technologií
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Groupe Polyphénols
https://schema.org/isbn	978-2-7380-1282-1
http://localhost/t...ganizacniJednotka	22330

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