About: Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S1877705812028573
Description	The work was focused on the analysis of different batches of the common pharmaceutical excipient lactose using inverse gas chromatography (IGC). Several batches of amorphous (spray dried) and crystalline form of lactose were studied. Surface properties represented by the surface energy and specific (acid-base) interactions between probes and analyzed samples shows batch variations and significant differences between manufacturers and technological processes. The second part of this work was focused on effect of relative humidity and temperature on stability of lactose. The variations of surface energy and specific interactions over time were studied. The changes in surface properties of two batches of lactose-amorphous and crystalline caused by higher relative humidity were measured by IGC. From measured values are obvious different chemical and physical properties of both lactose forms. Negative effect of higher temperature and air humidity lead to changes in surface energy and mainly rapid changes of electron-acceptor and electron-donor surface sites. Lactose monohydrate shows dramatic decrease in the surface energy and in the strength of electron-accepting sites on the contrary of spray dried where the acidity of surface increased. The work was focused on the analysis of different batches of the common pharmaceutical excipient lactose using inverse gas chromatography (IGC). Several batches of amorphous (spray dried) and crystalline form of lactose were studied. Surface properties represented by the surface energy and specific (acid-base) interactions between probes and analyzed samples shows batch variations and significant differences between manufacturers and technological processes. The second part of this work was focused on effect of relative humidity and temperature on stability of lactose. The variations of surface energy and specific interactions over time were studied. The changes in surface properties of two batches of lactose-amorphous and crystalline caused by higher relative humidity were measured by IGC. From measured values are obvious different chemical and physical properties of both lactose forms. Negative effect of higher temperature and air humidity lead to changes in surface energy and mainly rapid changes of electron-acceptor and electron-donor surface sites. Lactose monohydrate shows dramatic decrease in the surface energy and in the strength of electron-accepting sites on the contrary of spray dried where the acidity of surface increased. (en)
Title	Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography (en)
skos:prefLabel	Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography (en)
skos:notation	RIV/60461373:22310/12:43894827!RIV13-MSM-22310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM6046137301)
http://linked.open...iv/cisloPeriodika	September
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Zámostný, Petr Patera, Jan Bělohlav, Zdeněk Litva, Dušan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemické technologie
http://linked.open...dnocenehoVysledku	135108
http://linked.open...ai/riv/idVysledku	RIV/60461373:22310/12:43894827
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Increased humidity; Spray dried lactose; Lactose monohydrate; Inverse gas chromatography (en)
http://linked.open.../riv/klicoveSlovo	Increased humidity Inverse gas chromatography Lactose monohydrate Spray dried lactose
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[51C3D26A96F2]
http://linked.open...i/riv/nazevZdroje	Procedia Engineering
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	42
http://linked.open...iv/tvurceVysledku	Zámostný, Petr Patera, Jan Bělohlav, Zdeněk Bérová, Zuzana Litva, Dušan
http://linked.open...n/vavai/riv/zamer	Catalytic processes in chemistry and chemical technology
issn	1877-7058
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.proeng.2012.07.457
http://localhost/t...ganizacniJednotka	22310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software