About: Synthesis of Amminetrichloroplatinate(II) Ion

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Platinum complexes are commonly used as homogeneous catalysts or as precursors of supported metal catalysts and a very important group of platinum complexes are also used as precursors to fine chemicals. Potassium aminetrichloridoplatinate(II), KPt[(NH3)Cl3], is one such compound and it is a valuable precursor to many biologically active platinum complexes that are used as drugs with cytostatic activity, e.g. Picoplatin, LA-12 and Cycloplatam K[Pt(NH3)Cl3] is mainly prepared from cis-diamminedichloridoplatinate(II), cis Pt(NH3)2Cl2 that has itself been used as an anticancer drug, cisplatin, since 1978. The disadvantages of such a synthesis of K[Pt(NH3)Cl3] are the aforementioned biological activity of cis Pt(NH3)2Cl2 and very low yields of the key product. Alternative syntheses start from the less biologically active potassium tetrachloridoplatinate(II), K2PtCl4, but yields are lower than for the processes starting from cisplatin. The aim of this work was to find a new synthetic route for the pre Platinum complexes are commonly used as homogeneous catalysts or as precursors of supported metal catalysts and a very important group of platinum complexes are also used as precursors to fine chemicals. Potassium aminetrichloridoplatinate(II), KPt[(NH3)Cl3], is one such compound and it is a valuable precursor to many biologically active platinum complexes that are used as drugs with cytostatic activity, e.g. Picoplatin, LA-12 and Cycloplatam K[Pt(NH3)Cl3] is mainly prepared from cis-diamminedichloridoplatinate(II), cis Pt(NH3)2Cl2 that has itself been used as an anticancer drug, cisplatin, since 1978. The disadvantages of such a synthesis of K[Pt(NH3)Cl3] are the aforementioned biological activity of cis Pt(NH3)2Cl2 and very low yields of the key product. Alternative syntheses start from the less biologically active potassium tetrachloridoplatinate(II), K2PtCl4, but yields are lower than for the processes starting from cisplatin. The aim of this work was to find a new synthetic route for the pre (en)
Title	Synthesis of Amminetrichloroplatinate(II) Ion Synthesis of Amminetrichloroplatinate(II) Ion (en)
skos:prefLabel	Synthesis of Amminetrichloroplatinate(II) Ion Synthesis of Amminetrichloroplatinate(II) Ion (en)
skos:notation	RIV/60461373:22310/09:00022471!RIV10-GA0-22310___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(2A-2TP1/049), P(GD203/08/H032)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kačer, Petr Červený, Libor
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemické technologie
http://linked.open...dnocenehoVysledku	345094
http://linked.open...ai/riv/idVysledku	RIV/60461373:22310/09:00022471
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	platinum complexes; potassium amminetrichloroplatinate (II) (potassium amminetrichloriplatinate (II)); cisplatin; potassium tetrachloroplatinate (II) (tetrachloridoplatinate(II)) (en)
http://linked.open.../riv/klicoveSlovo	cisplatin platinum complexes potassium amminetrichloroplatinate (II) (potassium amminetrichloriplatinate (II)) potassium tetrachloroplatinate (II) (tetrachloridoplatinate(II))
http://linked.open...ontrolniKodProRIV	[CD71E831AABF]
http://linked.open...v/mistoKonaniAkce	Porto Carras, Chalkidiki Greece
http://linked.open...i/riv/mistoVydani	Thessaloniki
http://linked.open...i/riv/nazevZdroje	Clear Summer School
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Advanced catalytic processes and materials *Research and development of platinum(II) complexes with the different aminoligands and their synthetic platinum intermediates.
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Kačer, Petr Potucká, Lucie Červený, Libor Kysilka, Vladimír
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2009-05-24 (xsd:date)
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	CPERI-CERTH
https://schema.org/isbn	978-960-98231-1-1
http://localhost/t...ganizacniJednotka	22310

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