About: Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Seed extracts from six species of the genus Nigella (Family Ranunculaceae)—Nigella arvensis, Nigella damascena, Nigella hispanica, Nigella nigellastrum, Nigella orientalis, and Nigella sativa—obtained by successive extraction with n-hexane, chloroform, and methanol, were tested for their antimicrobial activity against 10 strains of pathogenic bacteria and yeast using the microdilution method as well as for anti-inflammatory properties by in vitro cyclooxygenase (COX)-1 and COX-2 assay. Chemical characterization of active extracts was carried out including free and fixed fatty acid analysis. Comparison of antimicrobial activity showed that N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial and yeast strains with minimum inhibitory concentration (MIC) values ranging from 0.25 to 1 mg/mL. With the exception of selective inhibitory action of n-hexane extract of N. orientalis on growth of Bacteroides fragilis (MIC = 0.5 mg/mL), we observed no a Seed extracts from six species of the genus Nigella (Family Ranunculaceae)—Nigella arvensis, Nigella damascena, Nigella hispanica, Nigella nigellastrum, Nigella orientalis, and Nigella sativa—obtained by successive extraction with n-hexane, chloroform, and methanol, were tested for their antimicrobial activity against 10 strains of pathogenic bacteria and yeast using the microdilution method as well as for anti-inflammatory properties by in vitro cyclooxygenase (COX)-1 and COX-2 assay. Chemical characterization of active extracts was carried out including free and fixed fatty acid analysis. Comparison of antimicrobial activity showed that N. arvensis chloroform extract was the most potent among all species tested, inhibiting Gram-positive bacterial and yeast strains with minimum inhibitory concentration (MIC) values ranging from 0.25 to 1 mg/mL. With the exception of selective inhibitory action of n-hexane extract of N. orientalis on growth of Bacteroides fragilis (MIC = 0.5 mg/mL), we observed no a (en)
Title	Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species (en)
skos:prefLabel	Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species (en)
skos:notation	RIV/60460709:41610/09:29797!RIV13-MSM-41610___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/09/P528), P(ME08070), Z(AV0Z50380511), Z(MSM6046070901)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kokoška, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Česká zemědělská univerzita v Praze / Institut tropů a subtropů
http://linked.open...dnocenehoVysledku	313805
http://linked.open...ai/riv/idVysledku	RIV/60460709:41610/09:29797
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antimicrobial activity, cyclooxygenase-1, cyclooxygenase-2, fatty acid composition, Nigella species (en)
http://linked.open.../riv/klicoveSlovo	antimicrobial activity fatty acid composition cyclooxygenase-2 Nigella species cyclooxygenase-1
http://linked.open...odStatuVydavatele	KR - Korejská republika
http://linked.open...ontrolniKodProRIV	[773861F166E0]
http://linked.open...i/riv/nazevZdroje	Journal of Medicinal Food
http://linked.open...in/vavai/riv/obor	GM
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Anti-inflammatory activity of plant quinones Biotechnological production of Vaccinium bracteatum and evaluation of its biological activity
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	12
http://linked.open...iv/tvurceVysledku	Kokoška, Ladislav Maršík, Petr Vaněk, Tomáš Landa, Přemysl Havlík, Jaroslav Klouček, Pavel
http://linked.open...n/vavai/riv/zamer	Mechanismy regulace růstu a vývoje rostlin na úrovni buněk, orgánů a celých organismů: fyziologické, genetické a molekulárně biologické základy Setrvalé zemědělství, kvalita zemědělské produkce, krajinné a přírodní zdroje.
issn	1096-620X
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	41610

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