About: Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The fungicide vinclozolin (VZ) is in use globally and known to disrupt reproductive function in male. The present study tested the hypothesis that VZ disrupts testicular function in goldfish (Carassius auratus) by affecting brain-pituitary-testis axis. Goldfish were exposed to 100, 400 and 800 µg/L VZ and 5 µg/L 17ß-estradiol (E2) for comparison. In VZ treated goldfish, 11-ketotesteosterone (11-KT) secretion was changed depending on dose and duration period of treatment. Following 7 days of exposure, 11-KT was decreased in goldfish exposed to 800 µg/L VZ, while it was increased in goldfish exposed to 100 µg/L VZ after 30 days of exposure. Circulating E2 level was unchanged in VZ treated goldfish, however the E2/11-KT ratio was increased in a dose-related manner. In E2 treated goldfish, circulatory 11-KT and E2 levels were decreased and increased respectively, which resulted in an increase in the E2/11-KT ratio. Exposure to VZ at 100 µg/L caused a significant increase in the circulatory luteinizing ho The fungicide vinclozolin (VZ) is in use globally and known to disrupt reproductive function in male. The present study tested the hypothesis that VZ disrupts testicular function in goldfish (Carassius auratus) by affecting brain-pituitary-testis axis. Goldfish were exposed to 100, 400 and 800 µg/L VZ and 5 µg/L 17ß-estradiol (E2) for comparison. In VZ treated goldfish, 11-ketotesteosterone (11-KT) secretion was changed depending on dose and duration period of treatment. Following 7 days of exposure, 11-KT was decreased in goldfish exposed to 800 µg/L VZ, while it was increased in goldfish exposed to 100 µg/L VZ after 30 days of exposure. Circulating E2 level was unchanged in VZ treated goldfish, however the E2/11-KT ratio was increased in a dose-related manner. In E2 treated goldfish, circulatory 11-KT and E2 levels were decreased and increased respectively, which resulted in an increase in the E2/11-KT ratio. Exposure to VZ at 100 µg/L caused a significant increase in the circulatory luteinizing ho (en)
Title	Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo (en)
skos:prefLabel	Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo (en)
skos:notation	RIV/60460709:41210/14:64302!RIV15-MSM-41210___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(EE2.3.20.0024), P(GAP503/12/1834), P(GP13-34049P), S
http://linked.open...iv/cisloPeriodika	N
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Alavi, Sayyed Mohammad Hadi
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Česká zemědělská univerzita v Praze / Fakulta agrobiologie, potravinových a přírodních zdrojů
http://linked.open...dnocenehoVysledku	2249
http://linked.open...ai/riv/idVysledku	RIV/60460709:41210/14:64302
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cytochrome P450 aromatase, Luteinizing hormone, Gonadotropin-releasing hormone, Sex steroids, Sex steroid receptors, Steroidogenic enzyme genes (en)
http://linked.open.../riv/klicoveSlovo	Gonadotropin-releasing hormone Sex steroids Cytochrome P450 aromatase Luteinizing hormone Sex steroid receptors Steroidogenic enzyme genes
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[5B48C9883403]
http://linked.open...i/riv/nazevZdroje	AQUATIC TOXICOLOGY
http://linked.open...in/vavai/riv/obor	GL
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Strengthening of research teams in FROV JU Identification of epigenetic biomarkers of male germ cell disorders linked to adverse environmental factors The toxicoproteomic: the potential for identification of new biomarkers in male fertility
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	155
http://linked.open...iv/tvurceVysledku	Alavi, Sayyed Mohammad Hadi Hatef, Azadeh Golshan, Mahdi Socha, Magdalena Gosiewski, Grzegorz Fontaine, Pascal Habibi, Hamid R. Milla, Sylvain Sokołowska-Mikołajczyk, Mirosława Zare, Ava
http://linked.open...ain/vavai/riv/wos	000342245300009
issn	0166-445X
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	41210

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software