About: Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The processes of oocyte growth, acquisition of meiotic competence and meiotic maturation are regulated by a large number of molecules. One of them could be calcineurin consisting of catalytic subunit A (A-alpha, A-beta, A-gama isoforms) and regulatory subunit B (B1, B2 isoforms). Calcineurin is involved in the meiotic maturation of oocytes in invertebrates or in lower vertebrates. In the mammalian oocytes, the possible role of calcineurin in the regulation of oocyte meiosis has not been clarified to date. In this study, to investigate the role of calcineurin during porcine oocyte growth, acquisition of meiotic competence and meiotic maturation, we analysed the expression and localisation of calcineurin subunits and the mRNA expression of calcineurin isoforms. Calcineurin was expressed in growing porcine oocytes, in fully grown oocytes and during their in vitro meiotic maturation. We found both subunits of calcineurin. Calcineurin A and calcineurin B were localised mainly in the cortex in all porcine The processes of oocyte growth, acquisition of meiotic competence and meiotic maturation are regulated by a large number of molecules. One of them could be calcineurin consisting of catalytic subunit A (A-alpha, A-beta, A-gama isoforms) and regulatory subunit B (B1, B2 isoforms). Calcineurin is involved in the meiotic maturation of oocytes in invertebrates or in lower vertebrates. In the mammalian oocytes, the possible role of calcineurin in the regulation of oocyte meiosis has not been clarified to date. In this study, to investigate the role of calcineurin during porcine oocyte growth, acquisition of meiotic competence and meiotic maturation, we analysed the expression and localisation of calcineurin subunits and the mRNA expression of calcineurin isoforms. Calcineurin was expressed in growing porcine oocytes, in fully grown oocytes and during their in vitro meiotic maturation. We found both subunits of calcineurin. Calcineurin A and calcineurin B were localised mainly in the cortex in all porcine (en)
Title	Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation (en)
skos:prefLabel	Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation (en)
skos:notation	RIV/60460709:41210/13:61554!RIV14-MSM-41210___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GAP502/10/0794), S, Z(MSM6046070901)
http://linked.open...iv/cisloPeriodika	3-4
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Hošková, Kristýna Jílek, František Žalmanová, Tereza Kučerová Chrpová, Veronika Chmelíková, Eva Tůmová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Česká zemědělská univerzita v Praze / Fakulta agrobiologie, potravinových a přírodních zdrojů
http://linked.open...dnocenehoVysledku	64103
http://linked.open...ai/riv/idVysledku	RIV/60460709:41210/13:61554
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pig, Oocyte, Growth period, Meiotic competence, Meiotic maturation, Calcineurin (en)
http://linked.open.../riv/klicoveSlovo	Calcineurin Growth period Meiotic competence Meiotic maturation Oocyte Pig
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[A606DF6043F6]
http://linked.open...i/riv/nazevZdroje	Animal Reproduction Science
http://linked.open...in/vavai/riv/obor	GG
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Acquisition of meiotic competence in pig oocytes - the effects of protein phosphatase calcineurin
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	141
http://linked.open...iv/tvurceVysledku	Jílek, František Kott, Tomáš Petr, Jaroslav Tůmová, Lenka Tichovská, Hana Chmelíková, Eva Hošková, Kristýna Kučerová Chrpová, Veronika Žalmanová, Tereza
http://linked.open...ain/vavai/riv/wos	000326422300007
http://linked.open...n/vavai/riv/zamer	Setrvalé zemědělství, kvalita zemědělské produkce, krajinné a přírodní zdroje.
issn	0378-4320
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	41210

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