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  • The beneficial effect of probiotic Escherichia coli strain Nissle 1917 (EcN) suggests the gut epithelium plays a basic role in immune interactions with bacteria. Contrary to other commensal strains of Escherichia coli, EcN profoundly modulates the gut barrier to elevate its resistance to microbial pathogens. The present review documents the properties of EcN that have led to the protection of gnotobiotic pigs against lethal enteric infections. This effect could be important in light of the growing number of acquired deficiencies that paralyze gut immunity in humans.
  • The beneficial effect of probiotic Escherichia coli strain Nissle 1917 (EcN) suggests the gut epithelium plays a basic role in immune interactions with bacteria. Contrary to other commensal strains of Escherichia coli, EcN profoundly modulates the gut barrier to elevate its resistance to microbial pathogens. The present review documents the properties of EcN that have led to the protection of gnotobiotic pigs against lethal enteric infections. This effect could be important in light of the growing number of acquired deficiencies that paralyze gut immunity in humans. (en)
Title
  • Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917
  • Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917 (en)
skos:prefLabel
  • Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917
  • Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917 (en)
skos:notation
  • RIV/60460709:41210/10:47616!RIV12-GA0-41210___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA523/07/0572), P(GA524/09/0365), S, Z(AV0Z50200510)
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  • 8
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  • 272337
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  • RIV/60460709:41210/10:47616
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  • Escherichia coli strain Nissle 1917, gut, innate immunity (en)
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  • US - Spojené státy americké
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  • [FA6BCE30EEA7]
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  • Nutrition Reviews
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  • 68
http://linked.open...iv/tvurceVysledku
  • Rada, Vojtěch
  • Šplíchalová, A.
  • Trebichavský, I.
  • Šplíchal, I.
http://linked.open...ain/vavai/riv/wos
  • 000280151900002
http://linked.open...n/vavai/riv/zamer
issn
  • 0029-6643
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/j.1753-4887.2010.00305.x
http://localhost/t...ganizacniJednotka
  • 41210
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