About: USING THE PIG’S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://vavtest.unob.cz/registr
Description	An integral part of the research and development of new antidotes against nerve agents (herein referred to as NAs) is the verification of their efficacy by means of in vitro tests. The purpose of these tests is to verify the ability of an antidote to protect cholinesterases from inhibition or to reactivate inhibited cholinesterases. For this purpose cholinesterases of different species and with a different degree of purification are traditionally used. Using mmobilized cholinesterases proves to be new and advantageous for a number of reasons. The authors of the presented work verified the usability of Detehit detector (Oritest Praha Ltd) containing the pig’s brain cetylcholinesterase for this purpose. In this article we see the results of tests focused on verifying the effect of different reaction conditions on the activity of acetylcholinesterase, especially with regard to reproducibility of these measurements. An integral part of the research and development of new antidotes against nerve agents (herein referred to as NAs) is the verification of their efficacy by means of in vitro tests. The purpose of these tests is to verify the ability of an antidote to protect cholinesterases from inhibition or to reactivate inhibited cholinesterases. For this purpose cholinesterases of different species and with a different degree of purification are traditionally used. Using mmobilized cholinesterases proves to be new and advantageous for a number of reasons. The authors of the presented work verified the usability of Detehit detector (Oritest Praha Ltd) containing the pig’s brain cetylcholinesterase for this purpose. In this article we see the results of tests focused on verifying the effect of different reaction conditions on the activity of acetylcholinesterase, especially with regard to reproducibility of these measurements. (en)
Title	USING THE PIG’S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS – PART I USING THE PIG’S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS – PART I (en)
skos:prefLabel	USING THE PIG’S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS – PART I USING THE PIG’S BRAIN ACETYLCHOLINESTERASE IMMOBILIZED ON A TEXTILE FIBER TO TEST THE ANTIDOTES OF NERVE AGENT POISONINGS – PART I (en)
skos:notation	RIV/60162694:G45__/13:00498733!RIV14-MO0-G45_____
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Moravcová, Ivana Cabal, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Ústav ochrany proti zbraním hromadného ničení
http://linked.open...dnocenehoVysledku	113188
http://linked.open...ai/riv/idVysledku	RIV/60162694:G45__/13:00498733
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Detehit detector; cholinesterase; nerve agents; reactivator (en)
http://linked.open.../riv/klicoveSlovo	cholinesterase Detehit detector nerve agents reactivator
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[EF3821B12E82]
http://linked.open...i/riv/nazevZdroje	Vojenské zdravotnické listy
http://linked.open...in/vavai/riv/obor	KA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	81
http://linked.open...iv/tvurceVysledku	Cabal, Jiří Moravcová, Ivana Šandová, Jitka
issn	0372-7025
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	G45

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