About: Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides

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About: Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ingentaconnect.com/content/ben/mrmc/2013/00000013/00000014/art00011
Description	Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment. Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment. (en)
Title	Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides (en)
skos:prefLabel	Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides (en)
skos:notation	RIV/60162694:G44__/13:43874937!RIV14-MZ0-G44_____
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(LH13009), P(NT12062)
http://linked.open...iv/cisloPeriodika	14
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Jun, Daniel Pohanka, Doc. RNDr. PhD, Miroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	100407
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/13:43874937
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	toxicity; oxime; protection; reactivator; organophosphate; antidote; treatment; prophylaxis; poisoning; pesticides; nerve agents; butyrylcholinesterase; Acetylcholinesterase (en)
http://linked.open.../riv/klicoveSlovo	organophosphate Acetylcholinesterase nerve agents prophylaxis protection toxicity treatment butyrylcholinesterase pesticides oxime reactivator poisoning antidote
http://linked.open...odStatuVydavatele	AE - Stát Spojené arabské emiráty
http://linked.open...ontrolniKodProRIV	[1C56BC9A74CE]
http://linked.open...i/riv/nazevZdroje	Mini Reviews in Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	The research of modified cholinesterase reactivators for organophosphorus pesticide poisoning treatment Preparation and biological evaluation of new therapeutics against to pesticides
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Kuča, Kamil Musílek, Kamil Pohanka, Miroslav Žďárová Karasová, Jana Jun, Daniel Soukup, Ondřej
http://linked.open...ain/vavai/riv/wos	000328088300011
issn	1389-5575
number of pages	14 (xsd:int)
http://bibframe.org/vocab/doi	10.2174/13895575113136660108
http://localhost/t...ganizacniJednotka	G44

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