About: Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up     Goto   Sponge   NotDistinct   Permalink

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  • Objective The objective of this study was to assess the mid-term effects of cardiac resynchronization therapy on systolic function and remodelling of the right ventricle in clinical responders and non-responders. Methods A biventricular system was implanted between July 2005 and May 2008 in 58 patients with heart failure NYHA class II-IV. At baseline, three and 15 months after implantation, the following parameters were determined: NYHA class, quality of life, six-minute walk test, echocardiography including assessment of right ventricular systolic function by tricuspid annular plane systolic excursion and by pulsed tissue Doppler imaging (myocardial peak systolic velocity was measured at the tricuspid annulus). We also assessed the presence of ventricular dyssynchrony. Results There were no significant changes after three months of cardiac resynchronization therapy on right ventricular systolic function and remodelling in responders and non-responders. Among responders, we found a statistically significant improvement of right ventricular systolic function and also a significant decrease in the size of the right ventricle after 15 months of therapy (systolic excursion before therapy 17.8 +/- 4.0 mm vs 19.4 +/- 3.7 mm, P < 0.05, after therapy; peak systolic velocity initially 11.9 +/- 2.9 cm/s vs 12.7 +/- 3.2 cm/s; right ventricle size before therapy 29.3 +/- 5.0 mm vs 27.8 +/- 4.2 mm, P < 0.05, after therapy. These changes were not observed in non-responders. Conclusions Fifteen months after cardiac resynchronization therapy, we found a statistically significant improvement of right ventricular systolic function and a significant reduction of right ventricular size in responders to cardiac resynchronization therapy.
  • Objective The objective of this study was to assess the mid-term effects of cardiac resynchronization therapy on systolic function and remodelling of the right ventricle in clinical responders and non-responders. Methods A biventricular system was implanted between July 2005 and May 2008 in 58 patients with heart failure NYHA class II-IV. At baseline, three and 15 months after implantation, the following parameters were determined: NYHA class, quality of life, six-minute walk test, echocardiography including assessment of right ventricular systolic function by tricuspid annular plane systolic excursion and by pulsed tissue Doppler imaging (myocardial peak systolic velocity was measured at the tricuspid annulus). We also assessed the presence of ventricular dyssynchrony. Results There were no significant changes after three months of cardiac resynchronization therapy on right ventricular systolic function and remodelling in responders and non-responders. Among responders, we found a statistically significant improvement of right ventricular systolic function and also a significant decrease in the size of the right ventricle after 15 months of therapy (systolic excursion before therapy 17.8 +/- 4.0 mm vs 19.4 +/- 3.7 mm, P < 0.05, after therapy; peak systolic velocity initially 11.9 +/- 2.9 cm/s vs 12.7 +/- 3.2 cm/s; right ventricle size before therapy 29.3 +/- 5.0 mm vs 27.8 +/- 4.2 mm, P < 0.05, after therapy. These changes were not observed in non-responders. Conclusions Fifteen months after cardiac resynchronization therapy, we found a statistically significant improvement of right ventricular systolic function and a significant reduction of right ventricular size in responders to cardiac resynchronization therapy. (en)
Title
  • Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up
  • Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up (en)
skos:prefLabel
  • Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up
  • Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up (en)
skos:notation
  • RIV/60162694:G44__/12:43875339!RIV15-MO0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, V
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 125994
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/12:43875339
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • ventricular dyssynchrony; right ventricle; echocardiography; heart failure; Cardiac resynchronization therapy (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • BE - Belgické království
http://linked.open...ontrolniKodProRIV
  • [6D19BE1D210C]
http://linked.open...i/riv/nazevZdroje
  • Acta Cardiologica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 67
http://linked.open...iv/tvurceVysledku
  • Bláha, Václav
  • Haman, Luděk
  • Pařízek, Petr
  • Tauchman, Miloslav
  • Praus, Rudolf
http://linked.open...ain/vavai/riv/wos
  • 000305814400007
issn
  • 0001-5385
number of pages
http://bibframe.org/vocab/doi
  • 10.2143/AC.67.3.2160720
http://localhost/t...ganizacniJednotka
  • G44
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