About: Membrane rafts: a potential gateway for bacterial entry into host cells

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Pathogenic bacteria have developed various mechanisms to evade host immune defense systems. Invasion of pathogenic bacteria requires interaction of the pathogen with host receptors, followed by activation of signal transduction pathways and rearrangement of the cytoskeleton to facilitate bacterial entry. Numerous bacteria exploit specialized plasma membrane microdomains, commonly called membrane rafts, which are rich in cholesterol, sphingolipids and a special set of signaling molecules which allow entry to host cells and establishment of a protected niche within the host. This review focuses on the current understanding of the raft hypothesis and the means by which pathogenic bacteria subvert membrane microdomains to promote infection. Pathogenic bacteria have developed various mechanisms to evade host immune defense systems. Invasion of pathogenic bacteria requires interaction of the pathogen with host receptors, followed by activation of signal transduction pathways and rearrangement of the cytoskeleton to facilitate bacterial entry. Numerous bacteria exploit specialized plasma membrane microdomains, commonly called membrane rafts, which are rich in cholesterol, sphingolipids and a special set of signaling molecules which allow entry to host cells and establishment of a protected niche within the host. This review focuses on the current understanding of the raft hypothesis and the means by which pathogenic bacteria subvert membrane microdomains to promote infection. (en)
Title	Membrane rafts: a potential gateway for bacterial entry into host cells Membrane rafts: a potential gateway for bacterial entry into host cells (en)
skos:prefLabel	Membrane rafts: a potential gateway for bacterial entry into host cells Membrane rafts: a potential gateway for bacterial entry into host cells (en)
skos:notation	RIV/60162694:G44__/10:00002242!RIV11-GA0-G44_____
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/07/0226), P(OVUOFVZ200808), Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Kročová, Zuzana Červený, Lukáš Stulík, Jiří Härtlová, Anetta Hubálek, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	270314
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/10:00002242
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	host - pathogen interaction; intracellular bacteria; membrane rafts (en)
http://linked.open.../riv/klicoveSlovo	host intracellular bacteria membrane rafts
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1D4D2CE6FBF9]
http://linked.open...i/riv/nazevZdroje	Microbiology and Immunology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of B-cell interaction with intracellular pathogen Francisella tularensis. Development of new prophylactic tools against Francisella tularensis infection
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Hubálek, Martin Härtlová, Anetta Kročová, Zuzana Stulík, Jiří Červený, Lukáš
http://linked.open...ain/vavai/riv/wos	000276351900007
http://linked.open...n/vavai/riv/zamer	Zdravotnická problematika ZHN
issn	0385-5600
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	G44

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