About: Prophylaxis against nerve agents

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Prophylaxis against nerve agent intoxication is based on various approaches: keeping acetylcholinesterase intact (protection of cholinesterases) is a basic requirement for effective prophylaxis. The use of pyridostigmine alone or pyridostigmine with benactyzine and trihehyphenidyle (PANPAL) is typical example. Detoxification realised by administration of the enzymes splitting the organophosphate or evaluating specific enzymes (cholinesterases) is another possibility (stoichiometric and catalytic scavengers). Equine butyrylcholinesterase is an example of stoichiometric scavenger. The antidotes currently used for the treatment of organophosphate poisoning including reactivators are to be tested as prophylactics. As a result of this research, prophylactic antidote TRANSANT (transdermal patch containing HI-6) was developed as the prophylactic mean and introduced into the Czech Armed Forces. Prophylaxis against nerve agent intoxication is based on various approaches: keeping acetylcholinesterase intact (protection of cholinesterases) is a basic requirement for effective prophylaxis. The use of pyridostigmine alone or pyridostigmine with benactyzine and trihehyphenidyle (PANPAL) is typical example. Detoxification realised by administration of the enzymes splitting the organophosphate or evaluating specific enzymes (cholinesterases) is another possibility (stoichiometric and catalytic scavengers). Equine butyrylcholinesterase is an example of stoichiometric scavenger. The antidotes currently used for the treatment of organophosphate poisoning including reactivators are to be tested as prophylactics. As a result of this research, prophylactic antidote TRANSANT (transdermal patch containing HI-6) was developed as the prophylactic mean and introduced into the Czech Armed Forces. (en)
Title	Prophylaxis against nerve agents Prophylaxis against nerve agents (en)
skos:prefLabel	Prophylaxis against nerve agents Prophylaxis against nerve agents (en)
skos:notation	RIV/60162694:G44__/09:00002123!RIV10-MO0-G44_____
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MO0FVZ0000501)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Jun, Daniel Fusek, Josef Kassa, Jiří Kuča, Kamil Bajgar, Jiří
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	337188
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/09:00002123
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nerve agents, prophylaxis; different prophylactic means (en)
http://linked.open.../riv/klicoveSlovo	nerve agents prophylaxis different prophylactic means
http://linked.open...ontrolniKodProRIV	[91828D4C9DA7]
http://linked.open...i/riv/mistoVydani	Kerala
http://linked.open...i/riv/nazevZdroje	Central and peripheral nervous system: effects of highly toxic organophosphates and their antidotes
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...v/pocetStranKnihy	151 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Bajgar, Jiří Kassa, Jiří Kuča, Kamil Fusek, Josef Jun, Daniel
http://linked.open...n/vavai/riv/zamer	Zdravotnická problematika ZHN
number of pages	12 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Research Signpost
https://schema.org/isbn	978-81-308-0331-9
http://localhost/t...ganizacniJednotka	G44

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