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  • Kometový test je užitečná a citlivá metoda pro měření počtu jednořetězcových a dvou řertězcových zlomů v DNA. Citlivost metody je uznávána pouze v případě, že metoda je kalibrována. Metoda dokáže odhalit přítomnost několik tisíc zlomů DNA v buňce. Použití enzymů specifických pro dané léze DNA citlivost metody značně zvyšuje, ale specificita není absolutní. (cs)
  • The comet assay is a versatile and sensitive method for measuring single- and double-strand breaks in DNA. The sensitivity of the assay is only fully appreciated when it is calibrated: between one hundred and several thousand breaks per cell can be determined. By including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute.
  • The comet assay is a versatile and sensitive method for measuring single- and double-strand breaks in DNA. The sensitivity of the assay is only fully appreciated when it is calibrated: between one hundred and several thousand breaks per cell can be determined. By including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute. (en)
Title
  • The comet assay: topical issues
  • Kometový test: aktuální otázky (cs)
  • The comet assay: topical issues (en)
skos:prefLabel
  • The comet assay: topical issues
  • Kometový test: aktuální otázky (cs)
  • The comet assay: topical issues (en)
skos:notation
  • RIV/60162694:G44__/08:00001950!RIV09-MZ0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR8563), P(NR8985)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 360436
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/08:00001950
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • comet assay, single-strand breaks; DNA repair (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [C9B4BAC1F5AF]
http://linked.open...i/riv/nazevZdroje
  • Mutagenesis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 23
http://linked.open...iv/tvurceVysledku
  • Štětina, Rudolf
  • Brunborg, Gunnar
  • Collins, Andrew R.
  • Gaiva, Isabel
  • Giovannelli, Lisa
  • Kruszewski, Marcin
  • Oscoz1, Amaia Azqueta
  • Smith, Catherine C.
http://linked.open...ain/vavai/riv/wos
  • 000255523200001
issn
  • 0267-8357
number of pages
http://localhost/t...ganizacniJednotka
  • G44
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