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  • Farmakokinetika látky K203 - v současnosti syntetizovaného bispyridiniového oximu - byla zkoumána pomocí RP-HPLC. K203 obsah sérových vzorků bylo monitorováno pomocí HPLC-UV při 286 nm. Nízká koncentrace K203 ve vzorcích mozku, očí a cerebrospinální tekutiny byly rovněž určeny. Kvantitativní zhodnocení bylo umožněno amperometrickým detektorem. (cs)
  • The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentration of K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector.
  • The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentration of K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector. (en)
Title
  • HPLC study of the pharmacokinetics of K-203
  • HPLC studie farmakokinetiky látky K-203 (cs)
  • HPLC study of the pharmacokinetics of K-203 (en)
skos:prefLabel
  • HPLC study of the pharmacokinetics of K-203
  • HPLC studie farmakokinetiky látky K-203 (cs)
  • HPLC study of the pharmacokinetics of K-203 (en)
skos:notation
  • RIV/60162694:G44__/08:00001930!RIV09-GA0-G44_____
http://linked.open...avai/riv/aktivita
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  • P(GP305/07/P162)
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  • 4
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  • 370773
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  • RIV/60162694:G44__/08:00001930
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  • HPLC; K-203; pharmacokinetics; serum; brain; CSF; eyes (en)
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  • PL - Polská republika
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  • [9F80A8817A51]
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  • Acta Chromatographica
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  • 20
http://linked.open...iv/tvurceVysledku
  • Kuča, Kamil
  • Musílek, Kamil
  • Kalasz, H.
  • Szegi, P.
  • Tekes, K.
  • Laufer, L.
issn
  • 1233-2356
number of pages
http://localhost/t...ganizacniJednotka
  • G44
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