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Description
| - Specific markers for Coxiella burnetii (C.b.) isolates RSA 493, Priscilla, and BUD were detected using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). The method revealed noticeable differences in the ion signal profiles of the isolates in the mass range of 318 kDa. The number of characteristic ions for RSA 493, BUD, and Priscilla was 24, 15, and 7, respectively. The specific markers were compared against C.b. database using the Tag-Ident proteomics tool. For the isolates RSA 493, Priscilla and BUD there were identified 11, 5 and 3 potential biomarkers, respectively. This method represents a powerful tool for the rapid, sensitive, and differential characterization of C.b. isolates and is a good candidate for phyloproteomic approaches.
- Specific markers for Coxiella burnetii (C.b.) isolates RSA 493, Priscilla, and BUD were detected using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). The method revealed noticeable differences in the ion signal profiles of the isolates in the mass range of 318 kDa. The number of characteristic ions for RSA 493, BUD, and Priscilla was 24, 15, and 7, respectively. The specific markers were compared against C.b. database using the Tag-Ident proteomics tool. For the isolates RSA 493, Priscilla and BUD there were identified 11, 5 and 3 potential biomarkers, respectively. This method represents a powerful tool for the rapid, sensitive, and differential characterization of C.b. isolates and is a good candidate for phyloproteomic approaches. (en)
- Specifické C. burnetii márkery izolátů RSA 493, Priscilla, a BUD byly detekovány MALDI-TOF hmotnostní spekrometrií. Metoda odhalila nápadné rozdíly v profilech iontových signálů v hmotnostním rozsahu 318 kDa. Počet charakteristických iontů pro kmeny RSA 493, BUD a Priscilla byly 24, 15 a 7. Specifické márkery byly porovnány proti C. burnetii databázi použitím Tag-Ident proteomickým nástrojem. Pro izoláty RSA 493, Priscilla a BUD byly identifikováno 11, 5 a 3 potenciální biomárkery. Tato metoda představuje výkonný nástroj pro rychlou, citlivou a rozlišující charakterizaci izolátů C. burnetii a vhodné kandidáty pro fyloproteomické přístupy. (cs)
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Title
| - Detekce MALDI-TOF hmotnostní spektrometrií specifických spektrálních márkerů izolátů Coxiella burnetii (cs)
- Detection of specific spectral markers of Coxiella burnetii isolates by MALDI-TOF mass spectrometry
- Detection of specific spectral markers of Coxiella burnetii isolates by MALDI-TOF mass spectrometry (en)
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skos:prefLabel
| - Detekce MALDI-TOF hmotnostní spektrometrií specifických spektrálních márkerů izolátů Coxiella burnetii (cs)
- Detection of specific spectral markers of Coxiella burnetii isolates by MALDI-TOF mass spectrometry
- Detection of specific spectral markers of Coxiella burnetii isolates by MALDI-TOF mass spectrometry (en)
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skos:notation
| - RIV/60162694:G44__/07:00001856!RIV08-MO0-G44_____
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G44__/07:00001856
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - bacteria; mass spectrometry; proteome; biomarkers (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hernychová, Lenka
- Skultety, L.
- Toman, Rudolf
- Bereghazyova, Eva
- Slaba, Katarina
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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