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Description
| - Limitací termické ablace jaterního parenchymu je krevní průtok, který ochlazuje zahřívané ložisko. Experimentálně prokázaný je význam uzávěru portální žíly, který je obtížně proveditelný perkutánně. Vliv uzávěru odtoku krve z jater na efektivitu RFA není dosud experimentálně ověřen. Cílem práce je v experimentu na zvířeti prokázat změny průtoku jaterním parenchymem a zvýšenou efektivitu radiofrekvenční ablace (RFA) v kombinaci s perkutánním balonovým uzávěrem retrohepatální dolní duté žíly (RhDDŽ). Experiment byl proveden na 10 jedincích prasete domácího. Zvířata byla rozdělena do dvou skupin podle 2 protokolů RFA. Skupina A (n = 5) s dobou RFA do dosažení cílové teploty 105 oC, skupina B (n = 5) s konstantním časem RFA 8 minut. Pomocí peroperačního UZ vyšetření byly kvantifikovány změny průtoku jaterním parenchymem při uzávěru RhDDŽ. Dále byla vytvořena dvě ložiska RFA v jaterním parenchymu. Byl použit generátor RITA 1500X(R) a jehla StarBurst XLTM (Rita Medical System, Mountain View, USA) pro ablaci (cs)
- Heat loss induced by tissue vascular flow is one factor limiting radiofrequency tumor ablation (RFA) in the liver parenchyma. Decreasing the liver blood flow appears to be an interesting adjunct to RFA. It seems that manipulation of the portal blood inflow is the most important. However, the percutaneous portal vein occlusion is technically difficult. Complete blockage of the liver blood outflow (LBFO) by occluding the whole segment of the retrohepatic vena cava and its impact on RFA is not experimentally verified. The aim is to evaluate the feasibility of liver blood outflow occlusion and its impact on the effectiveness of RFA. The experiment was performed on 10 pigs. The animals were divided into groups A and B according to RFA protocol. In group A (n = 5) the RFA time was that taken to reach the target temperature of 105 oC, whereas group B (n = 5) had a constant RFA temperature of 105 oC and constant time of 8 min. The liver blood flow (LBF) was quantified using Doppler ultrasonography before LBFO
- Heat loss induced by tissue vascular flow is one factor limiting radiofrequency tumor ablation (RFA) in the liver parenchyma. Decreasing the liver blood flow appears to be an interesting adjunct to RFA. It seems that manipulation of the portal blood inflow is the most important. However, the percutaneous portal vein occlusion is technically difficult. Complete blockage of the liver blood outflow (LBFO) by occluding the whole segment of the retrohepatic vena cava and its impact on RFA is not experimentally verified. The aim is to evaluate the feasibility of liver blood outflow occlusion and its impact on the effectiveness of RFA. The experiment was performed on 10 pigs. The animals were divided into groups A and B according to RFA protocol. In group A (n = 5) the RFA time was that taken to reach the target temperature of 105 oC, whereas group B (n = 5) had a constant RFA temperature of 105 oC and constant time of 8 min. The liver blood flow (LBF) was quantified using Doppler ultrasonography before LBFO (en)
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Title
| - Dočasný uzávěr odtoku krve z jater zvyšuje efektivitu radiofrekvenční ablace. Experimentální studie (cs)
- Temporary liver blood outflow occlusion increases effectiveness of radiofrequency ablation in liver parenchyma. an experimental study
- Temporary liver blood outflow occlusion increases effectiveness of radiofrequency ablation in liver parenchyma. an experimental study (en)
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skos:prefLabel
| - Dočasný uzávěr odtoku krve z jater zvyšuje efektivitu radiofrekvenční ablace. Experimentální studie (cs)
- Temporary liver blood outflow occlusion increases effectiveness of radiofrequency ablation in liver parenchyma. an experimental study
- Temporary liver blood outflow occlusion increases effectiveness of radiofrequency ablation in liver parenchyma. an experimental study (en)
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skos:notation
| - RIV/60162694:G44__/07:00001828!RIV08-MO0-G44_____
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G44__/07:00001828
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Catheter ablation; neoplasm recurrence; local; instrumentation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Ferko, Alexander
- Šubrt, Zdeněk
- Dvořák, P.
- Tyčová, V.
- Ryska, M.
- Chovanec, V.
- Jon, B.
- Raupach, J.
- Hoffmann, P.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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